This article presents a guided-inquiry (GI) hands-on determination of Fe in food samples including plantains, spinach, lima beans, oatmeal, Frosted Flakes cereal (generic), tilapia fish, and chicken using flame atomic absorption spectroscopy (FAAS). The utility of the GI experiment, which is part of an instrumental analysis laboratory course,…

The North Carolina State University Biotechnology Program offers laboratory-intensive courses to both undergraduate and graduate students. In "Manipulation and Expression of Recombinant DNA," students are separated into undergraduate and graduate sections for the laboratory, but not the lecture, component. Evidence has shown that…

Our aim in this proposal is to use Faraday's law of induction as a simple lecture demonstration to measure the Earths magnetic field (B). This will also enable the students to learn about how electric power is generated from rotational motion. Obviously the idea is not original, yet it may be attractive in the sense that no sophisticated devices…

A piezoelectric material generates an electric potential across its surface when subjected to mechanical stress; conversely, the inverse piezoelectric effect describes the expansion or contraction of the material when subjected to some applied voltage. Piezoelectric materials are used in devices such as doorbell buzzers, barbeque igniters, and…

Microwave heating enhanced the rate of three reactions typically performed in our undergraduate organic chemistry laboratory: a Diels-Alder cycloaddition, a Wittig salt formation, and a Williamson ether synthesis. Ninety-minute refluxes were shortened to 10 min using a laboratory-grade microwave oven. In addition, yields improved for the Wittig…

First-year physics laboratories are often driven by a mix of goals that includes the illustration or discovery of basic physics principles and a myriad of technical skills involving specific equipment, data analysis, and report writing. The sheer number of such goals seems guaranteed to produce cognitive overload, even when highly detailed…

A hetero-Diels-Alder reaction that proceeds rapidly and only requires a simple filtration to purify the product is presented. The dienophile, 4-phenyl-1,2,4-triazoline-3,5-dione (PTAD), is prepared by the heterogeneous oxidation of 4-phenylurazole by the bromenium ion, Br[superscript +], generated in situ by the oxidation of potassium bromide by…

Lasers have transformed chemistry and the everyday world. Therefore, it is not surprising that undergraduate chemistry students are frequently exposed to fairly advanced laser techniques. The usual topics studied with lasers are molecular spectroscopy and chemical kinetics. Static and dynamic fluorescence experiments seem to be particularly…

In this article I support and extend the ideas presented by J. Brent Friesen in his article "Saying What You Mean; Teaching Mechanisms in Organic Chemistry" ("JCE" November, 2008). I emphasize "telling the truth" about proton transfers. The truth is that in aqueous acid most reactions are subject to "specific" acid catalysis: the only kinetically…

Students in the second-semester organic chemistry laboratory perform a Wittig reaction between butylidenetriphenylphosphorane (an ylide) and benzaldehyde and determine the relative percentages of the cis and trans isomers of the 1-phenyl-1-pentene product. Because of the highly reactive nature of this unstabilized ylide, students are introduced to…

Ronald J. Gillespie, the inventor of the Valence Shell Electron Pair Repulsion (VSEPR) model, relates how his career as researcher in Christopher Ingold's laboratories started. Gillespie developed a passion for chemistry and chemical education, searching for more appropriate and interesting ways to transmit the essential knowledge and enthusiasm…

Peptidomimetic compounds are increasingly important in drug-discovery applications. We introduce the synthesis of an N-substituted glycine oligomer, a bioactive "peptoid" trimer. The six-step protocol is conducted on solid-phase resin, enabling the synthesis to be performed by undergraduate organic chemistry students. This synthesis lab was…

In recent years, biofuel development and use has risen significantly. This undergraduate laboratory experiment educates students on the various alternative fuels that are being developed for automotive applications and the advantages and disadvantages of each. Students replicate commercially available alternative fuels, E85 and biodiesel, as well…

In this experiment, the concentrations of copper and zinc in brass are obtained by two methods. This experiment does not require advanced instrumentation, uses inexpensive chemicals, and can be easily carried out during a 3-h upper-level undergraduate laboratory. Pedagogically, the basic concepts of analytical chemistry in solutions, such as pH,…

Students commonly test the effects of chemical agents on the heart rate of the crustacean "Daphnia" magna, but the procedure has never been optimized. We determined the effects of three concentrations of ethanol, nicotine, and caffeine and of a control solution on heart rate in "Daphnia." Ethanol at 5% and 10% (v/v) reduced mean heart rate to…