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Direct linkHargadon, Kristian M. – Biochemistry and Molecular Biology Education, 2016
The flow of genetic information from DNA to RNA to protein, otherwise known as the "central dogma" of biology, is one of the most basic and overarching concepts in the biological sciences. Nevertheless, numerous studies have reported student misconceptions at the undergraduate level of this fundamental process of gene expression. This…
Descriptors: Genetics, Models, Teaching Models, Teaching Methods
Selvarajah, Geeta; Selvarajah, Susila – Biochemistry and Molecular Biology Education, 2016
Students frequently expressed difficulty in understanding the molecular mechanisms involved in chromosomal recombination. Therefore, we explored alternative methods for presenting the two concepts of the double-strand break model: Holliday junction and heteroduplex formation, and Holliday junction resolution. In addition to a lecture and…
Descriptors: Genetics, Molecular Structure, Scientific Concepts, Models
Green Snyder, LeeAnne; D'Angelo, Debra; Chen, Qixuan; Bernier, Raphael; Goin-Kochel, Robin P.; Wallace, Arianne Stevens; Gerdts, Jennifer; Kanne, Stephen; Berry, Leandra; Blaskey, Lisa; Kuschner, Emily; Roberts, Timothy; Sherr, Elliot; Martin, Christa L.; Ledbetter, David H.; Spiro, John E.; Chung, Wendy K.; Hanson, Ellen – Journal of Autism and Developmental Disorders, 2016
The 16p11.2 duplication (BP4-BP5) is associated with Autism Spectrum Disorder (ASD), although significant heterogeneity exists. Quantitative ASD, behavioral and neuropsychological measures and DSM-IV diagnoses in child and adult carriers were compared with familial non-carrier controls, and to published results from deletion carriers. The 16p11.2…
Descriptors: Pervasive Developmental Disorders, Developmental Disabilities, Psychiatry, Statistical Analysis
Prevost, Luanna B.; Smith, Michelle K.; Knight, Jennifer K. – CBE - Life Sciences Education, 2016
Previous work has shown that students have persistent difficulties in understanding how central dogma processes can be affected by a stop codon mutation. To explore these difficulties, we modified two multiple-choice questions from the Genetics Concept Assessment into three open-ended questions that asked students to write about how a stop codon…
Descriptors: Science Instruction, Genetics, Scientific Concepts, Scoring
Thomas, Michael S. C.; Davis, Rachael; Karmiloff-Smith, Annette; Knowland, Victoria C. P.; Charman, Tony – Developmental Science, 2016
This article outlines the "over-pruning hypothesis" of autism. The hypothesis originates in a neurocomputational model of the regressive sub-type (Thomas, Knowland & Karmiloff-Smith, 2011a, 2011b). Here we develop a more general version of the over-pruning hypothesis to address heterogeneity in the timing of manifestation of ASD,…
Descriptors: Autism, Pervasive Developmental Disorders, Computer Simulation, Symptoms (Individual Disorders)
Patricia J. Friedrichsen; Troy D. Sadler; Kerri Graham; Pamela Brown – International Journal of Designs for Learning, 2016
In this design case, we describe our work to design and develop a socio-scientific issue (SSI) based unit of instruction for use in high school biology. Our team includes university based science educators, an experienced classroom teacher, and a microbiologist. The unit focuses on antibiotic resistant bacteria as a context for student exploration…
Descriptors: Science and Society, Secondary School Science, Science Instruction, Instructional Design
García, Justin D. – Multicultural Perspectives, 2013
The purpose of this article is to examine the ambiguous positioning of persons and groups, particularly Latinos, who are neither "White" nor "Black" (as these terms are popularly understood) in an American society that has traditionally constructed race in a dichotomous and rigid fashion. The author also draws on his own lived…
Descriptors: Ethnicity, Hispanic Americans, Race, Genetics
Viding, Essi – Journal of Child Psychology and Psychiatry, 2013
Psychologists and psychiatrists have long been aware that individuals differ in their response to environmental stressors. It is equally apparent that whilst positive or corrective environmental factors help some individuals, others seem to benefit little, if at all. To make the matters even more interesting (at least for a researcher who is…
Descriptors: Psychiatry, Stress Variables, Environmental Influences, Genetics
Militello, Kevin T. – Biochemistry and Molecular Biology Education, 2013
Epigenetic inheritance is the inheritance of genetic information that is not based on DNA sequence alone. One type of epigenetic information that has come to the forefront in the last few years is modified DNA bases. The most common modified DNA base in nature is 5-methylcytosine. Herein, we describe a laboratory experiment that combines…
Descriptors: Genetics, Heredity, Laboratory Experiments, Science Experiments
Bartol, Jordan – Science & Education, 2013
Personalized genomics companies (PG; also called "direct-to-consumer genetics") are businesses marketing genetic testing to consumers over the Internet. While much has been written about these new businesses, little attention has been given to their roles in science communication. This paper provides an analysis of the gene concept…
Descriptors: Genetics, Scientific Research, Scientific Concepts, Sciences
Vandervoort, Frances S. – American Biology Teacher, 2013
Oscar Riddle, born in Indiana in 1877, was an ardent evolutionist and a key player in the founding of the National Association of Biology Teachers in 1938. He studied heredity and behavior in domestic pigeons and doves with Charles O. Whitman of the University of Chicago, received his Ph.D. in zoology in 1907, and in 1912 began a long career at…
Descriptors: Scientists, Evolution, Genetics, Animals
LaFreniere, Peter; MacDonald, Kevin – Developmental Review, 2013
Recent advances in molecular genetics and epigenetics are reviewed that have major implications for the bio-behavioral sciences and for understanding how organisms adapt to their environments at both phylogenetic and ontogenic levels. From a post-genomics perspective, the environment is as crucial as the DNA sequence for constructing the…
Descriptors: Genetics, Behavioral Sciences, Behavior Development, Adjustment (to Environment)
Dipla, K.; Zafeiridis, A.; Papadopoulos, S.; Koskolou, M.; Geladas, N.; Vrabas, I. S. – Research in Developmental Disabilities: A Multidisciplinary Journal, 2013
The aim was to investigate the hemodynamic responses to isometric handgrip exercise (HG) and examine the role of the muscle metaboreflex in the exercise pressor response in individuals with intellectual disability (IID) and non-disabled control subjects. Eleven males with mild-moderate intellectual disabilities and eleven non-disabled males…
Descriptors: Control Groups, Metabolism, Males, Mental Retardation
Szeberenyi, Jozsef – Biochemistry and Molecular Biology Education, 2013
The experiment described in this test was aimed at identifying DNA repair proteins in human and yeast cells. Terms to be familiar with before you start to solve the test: DNA repair, germline mutation, somatic mutation, inherited disease, cancer, restriction endonuclease, radioactive labeling, [alpha-[superscript 32]P]ATP, [gamma-[superscript…
Descriptors: Genetics, Science Experiments, Multiple Choice Tests, Problem Solving
Bremner, Andrew J.; Caparos, Serge; Davidoff, Jules; de Fockert, Jan; Linnell, Karina J.; Spence, Charles – Cognition, 2013
Western participants consistently match certain shapes with particular speech sounds, tastes, and flavours. Here we demonstrate that the "Bouba-Kiki effect", a well-known shape-sound symbolism effect commonly observed in Western participants, is also observable in the Himba of Northern Namibia, a remote population with little exposure to…
Descriptors: Foreign Countries, Acoustics, Perception, Cultural Differences
