Survivors of brain injury from trauma and stroke often lose their sense of identity and face a series of lifelong obstacles that challenge their ability to integrate back into their communities and live meaningful and productive lives. Their stories provide powerful accounts of these challenges, which can inform clinical decision-making. Arguably,…

Both episodic memory and the key neural structure believed to support it, namely the hippocampus, are believed to undergo protracted periods of postnatal developmental. Critically however, the hippocampus is comprised of distinct subfields and circuits, and these circuits appear to mature at different rates (Lavenex and Banta Lavenex, 2013).…

The prelimbic cortex is argued to promote conditioned fear expression, at odds with appetitive research implicating this region in attentional processing. Consistent with an attentional account, we report that the effect of prelimbic lesions on fear expression depends on the degree of competition between contextual and discrete cues. Further, when…

Once a memory has formed, it is thought to undergo a gradual transition within the brain from short- to long-term storage. This putative process, however, also poses a unique problem to the memory system in that the same learned items must also be retrieved across broadly varying time scales. Here, we find that neurons in the ventrolateral…

Eyeblink conditioning given in the explicit presence of hippocampal ? results in accelerated learning and enhanced multiple-unit responses, with slower learning and suppression of unit activity under non-? conditions. Recordings from putative pyramidal cells during ?-contingent training show that pretrial ?-state is linked to the probability of…

Research about the brain has affected the education community and transformed the way that educators think about learning. The field of brain-based education looks at making connections between the latest research findings of neuroscientists and the most effective teaching practices for the enhancement of instruction and learning. Educators who…

The meaning, mechanism, and function of imitation in early infancy have been actively discussed since Meltzoff and Moore's (1977) report of facial and manual imitation by human neonates. Oostenbroek et al. (2016) claim to challenge the existence of early imitation and to counter all interpretations so far offered. Such claims, if true, would have…

The purpose of this study was to examine the role of phonological information on visual word recognition by using letter transposition effects. The Korean writing system gives a unique opportunity to investigate such phenomenon since the transposition of the beginning consonant (onset) and the end consonant (coda) of a certain syllable allows one…

In a sample of 37 adolescents and young adults with autism spectrum disorder (ASD) and 35 typically-developing controls (TDC), we investigated sensory symptoms by clinical measures, and Mismatch Negativity and P3a component at Fz with the frequency and duration oddball paradigms of event-related potentials. Results showed that compared to TDC, ASD…

During sentence processing, comprehenders form expectations regarding upcoming material, and may even predict a specific word. Previous event-related potential (ERP) studies have shown that disconfirmed predictions elicit a post-N400-positivity (PNP) with two distinct distributions. A frontal-PNP (f-PNP) is elicited when an unexpected but…

This study investigated the processes reflected in the widely observed N400 and P600 event-related potential (ERP) effects and tested the hypothesis that the N400 and P600 effects are functionally linked in a tradeoff relationship, constrained in part by individual differences in cognitive ability. Sixty participants read sentences, and ERP…

Technology is ubiquitous and takes many forms. Digital media consumption (e.g., television, video games, etc.) has increased significantly in its prevalence in our lives as well as in social acceptability. However, it has also been consistently implicated in poorer health outcomes. The extent to which cognitive functions are adversely affected by…

Early childhood is a time of extensive development in the brain and many of the body's biological systems that are critical for health. Learning and development during these early years can have a critical impact on future educational attainment, which is an important determinant of health. There are also other important aspects of early childhood…

The underlying neural mechanisms of implicit and explicit facial emotion recognition (FER) were studied in children and adolescents with autism spectrum disorder (ASD) compared to matched typically developing controls (TDC). EEG was obtained from N = 21 ASD and N = 16 TDC. Task performance, visual (P100, N170) and cognitive (late positive…

Allan N. Schore has served on the clinical faculty of the Department of Psychiatry and Biobehavioral Sciences at UCLA's David Geffen School of Medicine since 1996 and has maintained a private clinical practice for more than four decades. He has contributed significant research to the disciplines of interpersonal neurobiology, affective…