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ERIC Number: EJ1483537
Record Type: Journal
Publication Date: 2025-Jul
Pages: 13
Abstractor: As Provided
ISBN: N/A
ISSN: ISSN-0141-982X
EISSN: EISSN-1467-9639
Available Date: 2025-03-29
Beyond Statistical Power in Designing Clinical Trials: Shiny/R Apps to the Rescue
Pedro Sandoval1,2; Ester Vilaprinyó1,3; Rui Alves1,3; Albert Sorribas1,3
Teaching Statistics: An International Journal for Teachers, v47 n3 p187-199 2025
Medical students must understand statistical reasoning and sample size selection to design and interpret clinical trials. Beyond achieving sufficient statistical power, ensuring meaningful precision in treatment effect estimates is equally important. We developed free, interactive Shiny/R tools that let learners explore how varying sample sizes influence both power and precision in common study designs. As an example, we discuss a Shiny/R app that explores a two-group design with a binary outcome, allowing sample size computation, effect estimation, and simulation of experiments in different scenarios. By engaging with these simulations, students gain a practical grasp of clinical trial design, ultimately enhancing their research skills and improving patient care.
Wiley. Available from: John Wiley & Sons, Inc. 111 River Street, Hoboken, NJ 07030. Tel: 800-835-6770; e-mail: cs-journals@wiley.com; Web site: https://www.wiley.com/en-us
Publication Type: Journal Articles; Reports - Research
Education Level: Higher Education; Postsecondary Education
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A
Grant or Contract Numbers: N/A
Author Affiliations: 1Biomodels Research Group, University of Lleida & Institute of Biomedical Research of Lleida (IRBLleida), Lleida, Spain; 2Department of Mathematics and Statistics, Universidad Técnica Nacional (UTN), Balsa de Atenas, Costa Rica; 3Mathematical Systems & Synthetic Biology in Biomedicine and Biotechnology (MathSy2Bio), University of Lleida & Institute of Biomedical Research of Lleida (IRBLleida), Lleida, Spain