Describes the origins, definitions, tools, and principles of host-guest chemistry. Gives examples of chiral recognition in complexation, of partial transacylase mimics, of caviplexes, and of a synthetic molecular cell. (Author/RT)

Described are experiments to give students experience in the synthesis of peptides from amino acids and to use visible spectroscopy to measure a rate of reaction. The activities were designed for undergraduate courses. (RH)

Described is a laboratory activity to determine five unknown organic compounds. The procedures are designed to help students determine unknowns from a series of tests. (RH)

Described is an experiment that uses nuclear magnetic resonance to study the anomalous paramagnetism of iron(III) chelates. (RH)

Traces the growth in the industrial usage of organometallic chemistry from 1950 to 1977, pointing out that this growth involved the production of commodity chemicals. Indicates that one of the early successes of organometallic chemistry was the discovery of ethylene polymerization catalysts. (JN)

Outlines the development of the modern catalysts for propylene polymerization, considering the historical background; structure of titanium chloride catalysts; first-generation catalysts; cocatalysts; second-generation catalysts; catalysts morphology; and third-generation (supported catalysts). (JN)

Background information procedures used, results obtained, and instructional strategies are provided for an experiment using thin layer chromatography in conjunction with the synthesis of polystyrene. The experiment has been used and evaluated in a sophomore-level organic chemistry laboratory. (JN)

Discusses: (1) the architecture of expert systems; (2) features that distinguish expert systems from conventional programs; (3) conditions necessary to select a particular application for the development of successful expert systems; (4) issues to be resolved when building expert systems; and (5) limitations. Examples of selected expert systems…

Background information, procedures used, and typical results obtained are provided for an experiment that examines the ability of nuclear magnetic resonance (NMR) to distinguish between structural isomers via resonance multiplicities and chemical shifts. Reasons for incorporating the experiment into organic, analytical, or physical chemistry…

Suggests that pseudophase liquid chromatography, which uses aqueous surfactant solutions instead of organic solvents for the mobile phase, can be substituted for thin-layer chromatography in the introductory organic course. Outlines the method as it applies to common separations in the laboratory. (JN)

Discusses the development of physical organic chemistry: (1) before 1920; (2) from 1920 to 1930; (3) from 1930 to 1940; and (4) after 1940. Major accomplishments in these periods are noted. (JN)

Procedures are provided for a test that (1) demonstrates principles of derivatization with 2,4-dinitrophenylhydrazine; (2) is a thin layer chromatography experiment that visually demonstrates separation of colored compounds of different polarities; and (3) introduces microscale experimentation to students in sophomore organic chemistry…

The separation of derivatives of aliphatic compounds (2,4-dinitrophenylhydrazones) is used to introduce methods and techniques typically employed in thin layer chromatography and to provide a clear illustration of chromatographic principles in general. Procedures used in the separation are presented. (JN)

Although infrared spectroscopy is used primarily for qualitative identifications, it is possible to use it as a quantitative tool as well. The use of a standard curve to determine percent methanol in a 2,2,2-trifluoroethanol sample is described. Background information, experimental procedures, and results obtained are provided. (JN)

Background information, list of materials needed, and procedures used are provided for a demonstration involving the transformation of a hydrophobic liquid to a partially hydrophobic semisolid. Safety considerations are noted. (JN)