An experiment for the upper-division undergraduate biochemistry laboratory is described in which students investigate the influence of genetic variations of cytochrome P450 1A2 on drug metabolism, using caffeine as a model compound. Saliva samples from human subjects are characterized for a single-nucleotide polymorphism in the CYP1A2 gene…

This article describes the use of a spreadsheet to reinforce basic calculus that is expected of all university-level chemistry majors. The example provided shows a calculation using Excel to estimate, using a Riemann summation, the radiant exitance of a hot object using Planck's Law of Blackbody Radiation. The approach reinforces the elementary…

Mayo Clinic annually trains over 1,000 predoctoral students and postdoctoral research fellows in medicine and biomedical sciences. However, training opportunities are limited for those interested in teaching and mentoring undergraduates. Predoctoral students sought to provide practical, trainee-led, pedagogical learning opportunities. A survey…

Reported herein is a multidisciplinary laboratory experiment for advanced undergraduate students that includes elements of material synthesis, in the synthesis of cyclodextrin-containing metal-organic frameworks (CD-MOFs), and environmental chemistry, in the use of these MOFs for pollutant removal. This multiday laboratory experiment starts with…

Determination of thermostability of enzymes is of prime importance for their successful industrial applications and, yet, the published data has often been incompletely analyzed to assess the suitability of enzymes. It is possible to determine meaningful thermostability parameters from the routinely acquired data through a straightforward method…

Disrupting a gene to determine its effect on an organism's phenotype is an indispensable tool in molecular biology. Such techniques are critical for understanding how a gene product contributes to the development and cellular identity of organisms. The explosion of genomic sequencing technologies combined with recent advances in genome-editing…

Most chemistry educators agree that deep understanding of the nature of noncovalent interactions is essential for learning in chemistry. Yet decades of research have shown that students have persistent incorrect ideas about these interactions. We have worked in collaboration with a community of chemistry, biology, and biochemistry educators to…

Students use causal reasoning in their everyday lives to generate hypotheses as to why an event occurred, or to create predictions about future events. Also, causal reasoning skills are critical in the laboratory setting and are needed to (1) look for patterns in collected data, (2) determine if relationships exist between variables, and (3)…

Research investigating faculty and instructors' perception of teaching in discipline-oriented fields such as biology, chemistry and physics suggest that faculty hold diverse conceptions about teaching and learning. This study extended this work to a discipline at the interface between traditional physical science and life science fields,…

Curriculum planning should be a shared responsibility that involves students. To encourage higher education students to actively participate in their own education, we believe in the idea of engaging students as partners in learning and teaching. We have developed an Applied Curriculum Design in Science course at McMaster University that is aimed…

In this study, we analyzed the literature on teaching or learning on a topic in Earth science, environmental science, or climate change between 1995 and 2017. We investigated the length of the intervention, intervention setting and instructional level, instructional purpose, pedagogical framing and pedagogical methods (including what materials and…

The need for changing how science is taught and the expansion of undergraduate research experiences is essential to foster critical thinking in the Natural Sciences. Most faculty research programs only involve a small number of upper-level undergraduate students each semester. The course-based undergraduate research experience (CURE) model enables…

Flipped instruction is not new and the literature is extensive with examples of flipped courses. However, there is a lack of studies with a structured, methodical approach to flipped design, implementation, and evaluation of its effectiveness. An upper division geology course was flipped to allow focus on higher-level concepts, especially…

This study examines the effect of the flipped learning approach on academic achievement based on science and mathematics education fields with the meta-analysis method. For this purpose, including the different uses of the flipped learning approach in the literature; "Science Education & Academic Success & Flipped Classroom,"…

Enhancing student employability is a key aspect of any chemistry-based degree; however, embedding such activities in the curriculum is often challenging. Placements (internships in the USA) or experiential visits are the most widely used approach, but these are not always inclusive. Work-integrated learning (WIL), the practice of combining…