The syllabus for a refresher course on the physiology and biochemistry of receptors (presented at the 1983 American Physiological Society meeting) is provided. Topics considered include receptor regulation, structural/functional aspects of receptors for insulin and insulin-like growth factors, calcium channel inhibitors, and role of lipoprotein…

Presented is a possible approach to the classroom treatment of enzyme kinetics at the two-substrate level. Areas discussed include single substrate cases, two substrate cases, Cleland's rules, dead end inhibition, inhibitor complexing with more than one enzyme form, and product inhibition. (JN)

Describes a low-cost, senior-level, instrumental analysis experiment in which a home-made potassium tubular flow-through electrode is constructed and incorporated into a flow injection analysis system (FIA). Also describes experiments for evaluating the electrode's response properties, examining basic FIA concepts, and determining potassium in…

Argues against Hillman and Sartory's views of cell structure (EJ242880), pointing out that they are erroneous in their analysis of the motives and working methods of the scientific community, in their total rejection of information coming from electron microscopy, and in their claim that lysosomes and endoplasmic reticulum are imaginary. (DC)

Prospects for microbial technology are discussed including: (1) possible transfer of nitrogen-fixing ability directly from bacteria to plant; (2) increasing food needs met through single-cell proteins and fermentation; (3) microbial production of antibiotics; and (4) increased biogas production. (Author/JN)

Background information, laboratory procedures, and discussion of results are provided for experiments designed to familiarize students with the biochemistry of nicotinamide coenzymes and the chemistry involved in their reactions. In addition, students are exposed to ultraviolet (UV)-spectroscopy as a tool for investigating reaction mechanisms in…

A simple polarographic method is used to obtain continuous oxygen dissociation curves under a variety of conditions using a Clark oxygen electrode system. (Author/SK)

Provides background information on and experimental procedures for the preparation of sulcatol, an insect chemical. Includes physical properties of sulcatol derivatives and time required to complete experiments in the undergraduate organic chemistry laboratory. (Author/SK)

Provided are directions for culturing bacteria by using yoghurt as a culture medium. Yoghurt is a safe medium and results in an end product which may be eaten if desired. (PB)

The basic curricular structure and courses deemed necessary to podiatric medical education are outlined and their rationale explained. Specialties appropriate to podiatric practice, such as electrophysiology and cardiovascular physiology, are noted, and the sequence of coursework suggested. (MSE)

Spectroscopic studies on solutions and x-ray diffraction work on crystals lead to the conclusion that the Metrogen of the pyrimidine ring is preferentially protonated. The correct monoprotonated structures of thiamine and its 4-amino-pyrimidine synthetic precursor are presented. (BT)

Research is reviewed on the relationship of allergies including sensitivity to artificial food coloring to learning and behavior disabilities. (CL)

Amylose azure can be used as a chromogenic substrate for alpha-amylase in studying the effects of temperature and pH enzyme action. This is a model system which students can use to measure the energy of activation using the Arrhenius plot. (Author/BB)

An inexpensive DNA preparation is presented which starts with commercially available frozen packed bacterial cells. Methods for analyzing the DNA are also presented, along with physical chemical experiments which can be done using the purified DNA. (BB)

Presents an introduction to the articles in this monograph examining the genetic, biochemical, and psychological components of substance use disorder liability. Highlights the Center for Education and Drug Abuse Research's theory-guided comprehensive prospective research strategies and activities. (Contains 5 tables and 5 figures.) (GCP)