This action research study evaluated problem-based learning (PBL), traditional lecture, and a combination of PBL and lecture in an elective biochemistry course at a secondary school for gifted students. Lecture tended to wide content coverage, whereas understanding and retention was promoted by PBL. (Author/DB)

Describes an integrated problem-based learning experience for first-year medical students and assesses the effectiveness of the process in identifying basic science issues relevant to biochemical principles. (DDR)

Presents a science activity that integrates the disciplines of anatomy, physiology, genetics, and forensics in which students act as detectives unraveling evidence at a murder crime scene. This project is designed to enhance student interest by providing immediate application of these disciplines. (DKM)

Describes the biochemistry component of study to become a medical technologist in a Chilean university. Provides details of program structure, course content descriptions, and teaching strategies. (DDR)

The need to give high school students a more pragmatic grasp and understanding of technology, in addition to guidance concerning their career paths, is discussed. Described are the design, initiation, methods, topics and evaluation of this exploratory program. Recommendations for future implementation of similar programs are provided. (CW)

Develops an experiment that could be done in two- to three-hour blocks and does not rely on cold room procedures for most of the purification. Describes the materials, methods, and results of the purification of bovine heart lactate dehydrogenase using ammonium sulfate fractionation, dialysis, and separation using affinity chromatography and…

Described is an experiment which is designed to investigate the reaction of the protein ferrimyoglobin with fluoride. The activity uses readily available apparatus and the technique of optical absorbance for measurement of concentrations. Experimental design, procedures, and treatment of the equilibrium data are detailed. (CW)

Discusses a laboratory technique of enzyme purification by affinity chromatography as part of an undergraduate biochemical methodology course. Provides preparation details of the rat muscle homogenate and reagents. Proposes column requirements and assaying information. (MVL)

Explores neurochemical events in the extra cellular space of the brain by use of in vivo voltammetric microelectrodes. Reports dopamine concentrations and pathways, and discusses techniques used for analysis. Recognizes current problems and future directions for research. (ML)

Discusses the weaknesses and strengths of both term papers and short reports in fulfilling the supplementary goals of an introductory biochemistry course, namely, the development of written communication skills in concert with the presentation of course materials. (JJK)

Presented is a program where biochemistry students acquire hands-on experience through participation in an on-line computer literature search. The objectives of the program, example printouts, and a list of subtopics, authors, and sources used by students are included. (KR)

Proposes as a unifying theme for high school biology the question of "how chromosomes determine what we are." Describes a sequence of lessons in which students learn about proteins, enzymes, and amino acids. Includes three dry laboratory exercises to demonstrate the DNA sequences for sickle cell anemia and cystic fibrosis. (MDH)

Describes and evaluates a technique used in two science lecture courses (biochemistry and introductory meteorology), in which lectures were interspersed with frequent, brief discussions within spontaneously formed small groups. Some differences were found in the ways the two professors managed the technique, but both felt in-class participation…

Explores the ties between international environmental law and biochemistry with respect to genetically modified organisms, biodiversity, marine pollution, cancer biology, and pesticide contamination of food. Contains 30 references. (DDR)

Describes a biochemistry laboratory course in which the curriculum revolves around a single theme: the purification, characterization, and molecular biology of threonine dehydrogenase (TDH) from Escherechia coli. Lists examples of related class research projects. Contains 41 references. (WRM)