A method of estimating the solubilities of drugs in water is reported that is based on a principle applied in quantitative structure-activity relationships. This procedure involves correlation of partition coefficient values using the octanol/water system and aqueous solubility. (Author/MLW)

Reviews studies of regulation of nasal airway resistance (Rn). Describes methods of calculating Rn by measuring pressure-flow relationship. Data are presented on improved methods for measuring Rn and effects for expiratory and inspiratory Rn after topical application of phenylephrine nasal decongestant spray. (Author/SA)

Presents a reliable method for the sterilization of ciliates using common lab equipment and skills. A modified Glaser and Coria technique is used. (MA)

Describes the design of a new laboratory course that calls for experiments to be grouped in clusters. Each cluster has a unifying theme which gives coherence to the experiments. Other important guidelines in design were the use of computers, introduction of microscale chemistry, and use of instrumentation. Cluster examples include Carbon Is Number…

Uses trenoids, which are toothpicks colored with ink markers to represent a single taxa of organisms to illustrate ecological concepts in a student-centered learning environment. (YDS)

Describes a laboratory experiment on resistance to teach about evolution and issues of misuse of antimicrobial compounds. Investigates Escherichia coli's response to treatment of triclosan, a biocide used in consumer products. (Contains 12 references.) (YDS)

Describes a science activity on the importance of meiosis for variability. Uses a coin flip to demonstrate the random arrangement of genetic materials and explains how this results in zygotes with a new DNA combination. (YDS)

Describes the necking of polymer sheets that occurs when they are stretched. Discusses the effect and the mechanisms of necking. Lists four references. (YP)

Although the vast majority of articles cited by Jeanne Chall and Marie Carbo fit the patched-up program evaluation category, the outcomes of nine randomized field experiments are the best evidence available in the research literature. Systematic phonics is an example of the weak instructional treatments presently plaguing education. Includes 16…

Offers a unit of laboratory instruction for a general technology class that looks at ergonomics--the engineering science that seeks to prevent disorders caused by uncomfortable or stressful working conditions. The activity involves the measurement of body motions. (JOW)

Focuses on three habits associated with personal values and attitudes, and one habit associated with social skills of doing science. Illustrates four habits of mind, first through a story of modern scientific investigation, then as the basis of school laboratory science experience. Discusses implications related to integration of these four habits…

Describes a unit of laboratory work which was unusual in that the teacher's purpose was to develop students' understanding of the way scientific facts are established with little expectation that they would understand the science content involved in the experiments. The unit was very successful from both a cognitive and affective perspective.…

Presents an activity on liquid chromatography that demonstrates the influence of mobile phase polarity on the separation of dyes with different solubilities. (YDS)

Introduces an inquiry-based lab design in which students try to find evidence on a particular problem. Investigates the effects of decreases in the pH level on the environment. Includes students' hypotheses and research results. (YDS)

Describes a demonstration in which a teacher or student can relight a blown out candle from a burning candle held about 2-3 centimeters directly above it. (SAH)