The implementation of a laboratory exercise in an undergraduate chemistry course, where students perform a comparison of three different synthetic methods toward [Cu(Cl)(IPr)]-complexes (IPr = N,N'-bis(2,6-diisopropylphenyl)imidazol-2-ylidene), is described. The students are introduced to the continuous improvement of reactions in terms of green…

Gender equity is an area of concern within STEM, where women are underrepresented in education and career roles. Increasing the representation of women in STEM and removing negative gender stereotypes are necessary actions, both of which can be fostered during formal education through employability initiatives and in the workplace. This study…

The complexity of RNA cannot be fully expressed with the canonical A, C, G, and U alphabet. To date, over 170 distinct chemical modifications to RNA have been discovered in living systems. RNA modifications can profoundly impact the cellular outcomes of messenger RNAs (mRNAs), transfer and ribosomal RNAs, and noncoding RNAs. Additionally, aberrant…

The measurement of glucose through electrochemical methods is a great example to illustrate the practical application of electrochemistry. Although many students enrolled in chemistry classes are familiar with the glucose meter, only a few have delved into the underlying principles governing its operation. This experiment aims to address this gap…

Lidar remote sensing, which uses laser pulses to measure three-dimensional structure, has become essential across natural science disciplines. However, undergraduate students typically receive limited, if any, exposure to this technology and rarely have opportunities to experience it. Experiential and multi-modal courses may be ideal for…

Energy is a crosscutting concept in science, but college students often perceive a mismatch between how their biology and chemistry courses discuss the topic. The challenge of reconciling these disciplinary differences can promote faulty reasoning--for example, biology students often develop the incorrect idea that breaking bonds is exothermic and…

The 2011 "Vision & Change" report outlined several recommendations for transforming undergraduate biology education, sparking multiple pedagogical reform efforts. Among these was the Promoting Active Learning and Mentoring (PALM) network, an NSF-funded program that provided mentorship and training to instructors on implementing…

Formative assessment is a type of low-stakes assessment that can help reduce student anxiety and encourage students to engage in the course regularly. Formative assessment can also help instructors identify knowledge gaps. Students who had completed the first semester of a two-semester sophomore-level anatomy and physiology sequence were surveyed…

The study and analysis of enzymatic reactions are essential for characterizing various biological systems. As part of these procedures, it is important to understand how to quantify the biological activity of these proteins in terms of enzymatic activity. This work proposes a general equation for determining enzymatic activity based on…

Critical thinking is one of the most important sets of cognitive abilities and dispositions required for both scientists and global citizens. In this explorative study, we examine which critical thinking aspects are perceived as relevant by biology graduate students and in what ways they found these aspects important for their scientific work.…

Education in organic chemistry is highly reliant on molecular representations. Students abstract information from representations to make sense of submicroscopic interactions. This study investigates relationships between differing representations: bond-line structures, ball-and-stick, or electrostatic potential maps (EPMs), and predicting partial…

The effective implementation of evidence-based teaching (EBT) in large college courses benefits from the successful use of instructional teams. An instructional team's feedback allows instructors to act based on evidence of student learning, addressing students' needs. This feedback may be particularly important for novice instructors or…

Plant extracts and their components have been reported to have antimicrobial properties against phytopathogens. Although such properties could be harnessed for the development of new pathogen control strategies, there are no standardised methods for their assessment in different extracts. The laboratory exercise presented here involves the use of…

As the 21st century progresses, we are increasingly reminded of the importance of and need for green chemistry, which also leads to the corresponding need for green chemistry education. The UC Berkeley Department of Chemistry developed a green chemistry laboratory curriculum-the "General Chemistry Green Curriculum" ("GC[superscript…

The urea cycle disorder drug glycerol phenylbutyrate (Ravicti) is presently one of the most expensive medications in the United States, with annual costs estimated at $800,000 as of 2023. An expedient synthesis of this orphan drug was successfully adapted for the undergraduate organic chemistry laboratory. Activation of 4-phenylbutyric acid with…