An instructional research-like multiweek laboratory project for a second-semester introductory general chemistry laboratory course has been developed. The ultrasonic-assisted synthesis method using low cost commercial ultrasonic cleaners has the convenience of running multiple students' reactions simultaneously. Taking advantage of short reaction…

Single-outcome experiments are used in the undergraduate instructional laboratory, particularly for large lectures associated with multiple sections of instructional laboratories, due in large part to efficiencies associated with chemical purchases, experiment preparations, and assessments. Despite the practical advantages, single-outcome…

Curricular change within the chemistry curriculum is often difficult and slow, in part because there are numerous specific barriers to implementation. However, a larger issue is that the curriculum, and the institutions that it is connected with, are complex systems. In the implementation of a new green chemistry curriculum for the organic…

Chemistry educators have a responsibility to teach students about the essential role the field of chemistry has in a sustainable future for the planet. Chemical products, such as pharmaceuticals, plastics, electronics, agrochemicals, and building materials, all benefit society yet unintended consequences resulting from the production and use of…

A microwave-promoted synthesis of a carbocyclic curcuminoid has been developed for the undergraduate organic chemistry laboratory curriculum. The experiment features several teaching points: A novel Knoevenagel iminium-mediated condensation forms a highly conjugated, intensely colored natural product. Reaction occurs uniquely at the less acidic…

Reorienting organic chemistry laboratories with an emphasis on systemic thinking can only be beneficial to students. Addressing the challenges of climate change and the development of renewable resources with a fundamental reaction, such as the hydrogenation of an alkene, will allow students to see organic chemistry as a science beneficial to…

The main objective of the study was to determine Pre-service Chemistry Teachers' (PCTs) understanding of isomerism related concepts of Aliphatic Hydrocarbons (AHs). To get in-depth picture of PCTs understanding on isomerism related concepts of AHs, case study was employed. The sample for this study consisted of twelve participants selected from 87…

The Pre-College Summer Program at the University of Connecticut is designed to introduce upper-level high school students (rising juniors and seniors) to college life by allowing them to live on campus for a week while taking a college-level course. Within the context of this program, we developed a class designed to introduce high school students…

The advanced organic chemistry experiments describe the preparation of fused six-membered lactams to isoxazole and isoxazoline by employing Ugi four-component reaction (U-4CR) and intramolecular nitrile oxide cyclization (INOC) synthetic sequence. The experiments were carried out in 28 h (overnight for U-4CR) and 2 h (for INOC) using commercially…

A four week laboratory experiment was designed on the basis of a modification of the Weiss-Cook reaction for the preparation of "cis"-1,5-dimethylbicyclo[3.3.0]octane-3,7-dione. In general, this very versatile organic reaction involves a two-step process reacting biacetyl with 2 mol of dimethyl-1,3-acetonedicarboxylate to form…

This laboratory experiment visually demonstrates the advanced scientific concept of aggregation-induced emission (AIE) using hands-on learning methods. The experiment is divided into two parts: the first period consists of synthesis and isolation of the organic compound 2(TPA-O)-TPE using typical organic chemistry lab techniques; the second period…

The aim of this research was to establish the effects of argumentation and the quality of arguments related to history of the development of organic chemistry: (i) on the level of the pupils' knowledge about the composition, structure and general properties of organic compounds; and (ii) on their perception of the key aspect of NOS that scientific…

Organic Chemistry, Life, the Universe and Everything (OCLUE) is an undergraduate lecture-based organic chemistry course that has been transformed in line with the vision for science education set out by the 'Framework for K-12 Science Education: Practices, Crosscutting Concepts and Core Ideas' (National Research Council, 2012). OCLUE is designed…

Practical skills in chemistry are considered an essential outcome of an undergraduate chemistry degree. To achieve this, chemistry curricula are designated a substantial number of hours in teaching laboratories. However, the general method of a summative assessment of these sessions is through a written laboratory report and not through the actual…

Industrial drug discovery teams encompass scientists from multiple specialties and require participants to communicate effectively across disciplinary boundaries. In this paper, we present an undergraduate or graduate classroom simulation of this environment. Over a series of five workshops, student teams of mixed scientific backgrounds perform…