A laboratory experiment introducing the concept of chemical bioconjugation of proteins to undergraduate students in a therapeutically relevant context was developed. Initially, students installed an aldehyde functionality into a protein via the oxidation of the N-terminal threonine residue of the cholera toxin subunit B (CTB) protein, which was…

This research studied the impact of integrating virtual laboratories in chemistry lessons among 22 pre-service teachers who were enrolled in a Bachelor of Education program, focusing on middle and high school science. These participants were systematically divided into an experimental group (EG) and a control group. Both groups engaged in the same…

The dehydration of 2- or 4-methylcyclohexanol to obtain isomers of methylcyclohexene is a classic organic chemistry experiment. Students perform a distillation, collecting samples to analyze the progress of the reaction. The reaction produces a major product that can be explained on the basis of the regiochemistry of the [pi] bond formation for…

Developing students' self-study capacity is an urgent task of high schools in the current educational renovation period in Vietnam. This article presents research findings on developing self-study capacity for students through building and organizing teaching activities of 11th-grade organic chemistry project topics according to the blended…

Educational games can be used as an effective means of transferring knowledge in a fun way to complement education and training. The aim of the study was to develop a game and get students' opinions on the game that can be played in Organic Chemistry courses in order to teach the names of commonly used organic compounds with cyclic and aromatic…

This paper describes an innovative method to evaluate students' learning after teaching the topic of stereochemistry using molecular models in an organic chemistry course for second-year pharmacy students at Princess Nourah bint Abdulrahman University. This method is practical and relevant and directly measures the intended learning skills. It is…

Supporting students in building well-grounded explanations plays a crucial role in scientific practice. Research in organic chemistry education on students' mechanistic explanations, however, has revealed various challenges. When solving mechanistic tasks, students experience difficulties when (I) deriving implicit properties from structural…

The mechanism maps that guide student instruction in organic chemistry curricula are structural representations of bond-breaking and bond-making events that transform a reactant into a product. For students, these pathways represented by electron pushing formalism (EPF) can be challenging to navigate. For instructors, providing formative feedback…

The affordances given to a structured, timed, and proctored paper exam are not as readily applicable in a digital medium. Accordingly, the rapid shift from in-person to online enactments may have forced instructors to consider changing their assessment practices and priorities. As assessments convey strong implicit messages about "what…

A discovery-based undergraduate organic chemistry lab experiment has been developed in which students establish the diastereoselectivity of hydride reduction of the a-chiral ketone (±)-benzoin isopropyl ether to erythro and threo diastereomeric alcohols by two different reducing agents. Students achieve this goal by working collaboratively and…

In this communication the development of an online course on the topic "organic chemistry" for nonmajor chemistry students is described and discussed. For this online course, the existing classroom course was further developed. New elements such as podcasts, task navigators, and a forum for discussing the solving of tasks or problems…

We report a series of experiments based upon cinnamon oil that were developed to provide a practical integration of green and sustainable chemistry concepts for the organic chemistry laboratory. Five experiments centering around cinnamaldehyde as a green, plant-based chemical were performed by undergraduate students in a second-year organic…

This paper revisits the tie-dyeing process through a bioinspired and safer alternative to nucleophilic aromatic substitution (S[subscript N]Ar) reactions for an introductory organic chemistry laboratory. The simple and straightforward experiment provides students with an opportunity to gain practical experience in conducting a chemical reaction in…

Understanding resonance is essential to predict chemical reactivity and explain reaction mechanisms. Despite its importance in the organic curriculum, few studies have explored students' difficulties with this concept and faculty's instructional approaches to teaching it. The goals of this study are to address this gap in the literature by (1)…

Reported herein is a multidisciplinary experiment for senior-level undergraduate teaching laboratories in the synthesis of the analytes acetaminophen and phenacetin; the fabrication of paper-based devices, using eyeliner, acrylic spray paint, or wax-printing, for sensing of those analytes; and the use of the newly fabricated devices for successful…