Elevated whole blood serotonin (WB5-HT) is a well-replicated biomarker in autism spectrum disorder (ASD). Decreased platelet serotonin receptor 5-HT[subscript 2A] binding has been reported in ASD. WB5-HT levels and platelet 5-HT[subscript 2A] specific binding were obtained from 110 individuals with ASD and 18 controls. Individuals with ASD had…

Purpose: To analyze the contribution of physical measures and external load in the match-based internal load of elite soccer players. Methods: Twenty-three elite soccer players (n = 23, age 26.69 ± 3.93 years, body mass 78.04 ± 5.03 kg, height 178.04 ± 5.19 cm, body fat 10.98 ± 1.25%) from a first division soccer team of the Brazilian Championship…

Congenital adrenal hyperplasia (CAH) encompasses a range of autosomal recessive inherited enzyme deficiencies that impact cortisol biosynthesis pathways. Although reported as a rare and lifelong disorder, it holds chronic health risks for individuals that can influence menstruation. The purpose of this environmental scan and integrative literature…

Undergraduates use a spike sorting routine developed in Octave to analyze the spiking activity generated from mechanical stimulation of spines of cockroach legs with the inexpensive SpikerBox amplifier and the free software Audacity. Students learn the procedures involved in handling the cockroaches and recording extracellular action potentials…

While attention has consistently been shown to be biased toward threatening objects in experimental settings, our understanding of how attention is modulated when the observer is in an anxious or aroused state and how this ultimately affects behavior is limited. In real-world environments, automobile drivers can sometimes carry negative…

Introduction: Oral bisphosphonates are first-line agents for treating osteoporosis in men, but there are no studies regarding efficacy of oral bisphosphonates for treatment of osteoporosis in ambulatory male adults with intellectual disability. Methods: Nine adult males with intellectual disability and increased fracture risk had been treated with…

While metabolism is a fundamental process in physiology, the measurement of metabolism by living animals often requires specialized and expensive equipment. In 2016, I developed a novel laboratory exercise for animal physiology students where students were able to observe the effects of temperature and long-term temperature acclimation on the…

This paper describes the design, construction, and use of an open-source hardware and software tool intended to help Anatomy and Physiology students test their knowledge of muscle actions and joint movements. Orientation sensors are attached to a model skeleton to turn the skeleton into an interactive, physical model for teaching limb movements. A…

This study evaluated the reliability of the portable Lactate Pro 2 analyzer (LP2), and its validity compared to a laboratory-based analyzer, YSI 1500 Sport (YSI). Blood samples (n = 258) were collected during 44 graded incremental rowing tests, with data from 17 tests used to quantify load, heart rate, and oxygen consumption at lactate threshold.…

Many factors determine success in football. But the most important of these are the physical and physiological variables that determine the performance of football players. Meeting these physical and physiological needs is also based on training methods prepared following branch-specific neural, muscular, and metabolic parameters. In football, for…

Purpose: This study examined the physiological sport-specific demands (total distance, mean velocity, effective game time, and time in five velocity zones) in elite bandy players of offensive and defensive playing positions. Method: Data were collected with 10 Hz GPS-units in the Swedish Elite League during the season 2015/16. Ten male elite bandy…

Purpose: Patients with voice problems commonly report increased vocal effort, regardless of the underlying pathophysiology. Previous studies investigating vocal effort and voice production have used a range of methods to quantify vocal effort. The goals of the current study were to use the Borg CR100 effort scale to (a) demonstrate the relation…

Young children have an overall preference for child-directed speech (CDS) over adult-directed speech (ADS), and its structural features are thought to facilitate language learning. Many studies have supported these findings, but less is known about processing of CDS at short, sub-second timescales. How do the moment-to-moment dynamics of CDS…

With the advent of physiological computing systems, new avenues are emerging for the field of learning analytics related to the potential integration of physiological data. To this end, we developed a physiological computing infrastructure to collect physiological data, surveys, and browsing behavior data to capture students' learning journey in…

Regulation is a key concept for understanding the dynamics of metabolism in bacteria. This report outlines a simple laboratory experiment aimed at studying a key form of regulation in bacterial metabolism, exemplifying how microbes switch the flux of carbon towards alternative metabolic fates as a function of nutrient availability and according to…