A growing evidence base supports early intensive behavioral intervention (EIBI) for young children with autism spectrum disorder. We have found only one study exploring the outcome of EIBI for children with Rett syndrome, which reported little effect. It suggested that future studies should employ more fine-grained outcome measures. We provided…

The practice of communicating research findings to participants has been identified as important in the research ethics literature, but little research has examined empirically how this occurs and what research participants' views are in this regard. We interviewed 21 adults with cystic fibrosis who had previously participated in research and 2…

Identifying contingencies between constructs in a multi-faceted learning progression (LP) is a challenging task. Often, there is not enough evidence in the literature to support connections, and once identified, they are difficult to empirically test. Here, we use causal model search to evaluate how connections between ideas in a genetics LP…

Although social communication skills are commonly delayed in children with neurogenetic syndromes (NGS), skill profiles in very young children are largely under characterized, in part due to the lack of validated assessment measures appropriate for these populations. We addressed this gap by validating and applying a popular early social…

The limited and largely international, adult-based literature links "perfectionism" with both positive (achievement, life satisfaction) and negative (mental health difficulties, suicide) outcomes, both of which have relevance for education. This review identifies the key areas of agreement and conflict in the current research base,…

Children with neurogenetic syndromes (NGS) experience comorbid challenging behaviors and psychopathology. We examined challenging behaviors in 86 toddlers and preschoolers across three NGS [Angelman syndrome (AS), Prader--Willi syndrome (PWS), and Williams syndrome (WS)] and 43 low-risk controls (LRC), using the Child Behavior Checklist for Ages…

Results from a genome-wide association study (GWAS) can be used to generate a polygenic score (PGS), an individual-level measure summarizing identified genetic influence on a trait dispersed across the genome. For complex, behavioral traits, the association between an individual's PGS and their phenotype may contain bias (from geographic,…

Associative word learning, i.e., associating a word with an object, is an important building block of early word learning for TD infants. This study investigated the development of word-I object associations by TD infants and infants and toddlers with Williams syndrome (WS), a rare genetic disorder associated with delayed language and cognitive…

Typically developing (TD) infants adapt to the social world in part by shifting the focus of their processing resources to the relevant aspects of a visual scene. Any impairment in visual orienting may therefore constrain learning and development in domains such as language. However, although something is known about visual orienting in infants at…

The initial application of evolutionary theory to the universal practice of music-making in humans was at best marginal and at worst dismissive of non-Western musics. Darwin's biography defines an agenda for musicality in the emergence of human culture that is receiving considerable attention in several disciplines, presenting a robust case for…

The integration of scientific modeling into science teaching is key to the development of students' understanding of complex scientific phenomena, such as genetics. With this in mind, we conducted an introductory hands-on module during an outreach gene technology laboratory on the structure of DNA. Our module examined the influence of two model…

This study aims to categorize the scenarios designed on socio-scientific issues (SSIs) by prospective teachers who participated in an SSI-based instructional practice and to analyze these scenarios in terms of representing the nature of science (NOS) components. Sample of the study comprised SSI scenarios written by 30 third-year prospective…

Truncating variants of the "MAGEL2" gene, one of the protein-coding genes within the Prader-Willi syndrome (PWS) critical region on chromosome 15q11, cause Schaaf-Yang syndrome (SYS)--a neurodevelopmental disorder that shares several clinical features with PWS. The current study sought to characterize the neurobehavioral phenotype of SYS…

Conrad Hal Waddington's epigenetic landscape is now a central paradigm in evolutionary developmental biology. This article proposes that it should be adopted into middle-years (ages 11-16) biology curricula as a way of visualising the interactions of the genome with the environment. The epigenetic landscape is explained, with some biographical…

The rapidly growing field of epigenetics is now beginning to reveal how our genes are affected by environmental factors such as nutrition, exercise and stress. As it has such profound effects on our everyday lives, this article argues for the inclusion of epigenetics in the compulsory school science curriculum, and explores trainee science…