A laboratory experiment is detailed that entails the separation and derivatization of the artificial sweetener sucralose from a commercially available sweetener mixture. The experiment utilizes 1 g packets of a sucralose-based artificial sweetener and involves the separation of the synthetic sweetener from the more polar bulk additives by…

A reliable method for bleach-based alcohol oxidation has been developed. Use of sodium bisulfate as the acid additive in the reaction mixture eliminates the various problems associated with acetic acid, which has commonly been used for this type of oxidation. By conducting the reaction in an ethyl acetate/water two-phase reaction mixture,…

A laboratory experiment introducing the concept of chemical bioconjugation of proteins to undergraduate students in a therapeutically relevant context was developed. Initially, students installed an aldehyde functionality into a protein via the oxidation of the N-terminal threonine residue of the cholera toxin subunit B (CTB) protein, which was…

The reaction between hydrochloric acid and calcium carbonate to produce carbon dioxide gas is a popular and engaging experiment to illustrate chemical reactions that result in the production of gases. It also provides a useful model for teaching concepts related to the effects of concentration on reaction rates. Although a prepared hydrochloric…

In this work, we venture to show how careful use of a program for quantum chemical calculations (such as VASP) may enrich teaching in solid-state chemistry and how principles of thermodynamics contribute to a validation of phase diagrams and reaction pathways using the quasiternary system Li[subscript 2]O-Al[subscript 2]O[subscript…

Ion-selective electrodes are among the oldest and most important potentiometric sensing methods. In this experiment, students assemble their own reusable ion-selective electrode from glass tubes with an attached PTFE membrane, [(CH[subscript 3]CH[subscript 2]CH[subscript 2]CH[subscript 2]CH[subscript 2]CH[subscript 2]CH[subscript 2]CH[subscript…

Chemical thinking is a powerful tool for making sense of the material world and acting on it. But developing competence in chemical thinking may be challenging for students as it varies in several dimensions. This contribution seeks to guide and help chemistry educators in the design of learning experiences that support the development of…

This article highlights some of the challenges in explaining simple substituent effects on keto-enol equilibria, particularly to an undergraduate audience. Quantum-chemical calculations were performed to identify the role of intramolecular hydrogen bonding, inductive effects due to electron-withdrawing groups, and cross-conjugation on the…

Brewing science is an interdisciplinary course taught at many universities in both lecture- and lab-based modalities. The laboratory component of this class typically focuses on the brewing process from malted barley to beer. However, this ignores the malting process--an essential step in making beer, although one typically performed by maltsters…

Raman spectroscopy has become a popular analytical tool because of its ability to probe nondestructively and provide fingerprint information about materials. The advancements in the field of Raman spectroscopy and the expanding scope of applications warrant the introduction of the topic in the formal education curriculum. The introduction of Raman…

The educational game "Make or Take" is designed to approach the notoriously challenging topic of organic synthesis in an entertaining and engaging way. In this unique, two-part game, teams of students are given identical lists of several synthetic transformations, each requiring multiple steps to complete. During the first part of the…

With the enormous reliance on plastics in the world today, bisphenol A, an additive used in the synthesis of many plastics, such as polycarbonate, has been found almost everywhere in our environment including in soil, in natural waters, and inside organisms including humans. A multidisciplinary experiment is presented that involves using flatworms…

As the size of a nanoparticle is reduced, the fraction of surface atoms increases. It is interesting to note that various chemical and physical properties depend on the fraction of surface atoms. One of the most obvious questions that arise is how could one possibly estimate the fraction of surface atoms in a nanoparticle? Herein, we discuss…

The present technology report is aimed at demonstrating how the implementation of VR chemistry simulations of atomic structure enhances learning among students. MEL Chemistry VR lessons were incorporated into the classroom for 43 first-year undergraduate ITMO University students. The visualization techniques provided the learners with two…

The tradition of qualitative research drives much of chemistry education research activity. When performing qualitative studies, researchers must demonstrate the trustworthiness of their analysis so researchers and practitioners consuming their work can understand if and how the presented research claims and conclusions might be transferable to…