The intricate relationship between representational competence and content knowledge in organic chemistry has been widely debated, and the ways in which representations contribute to task difficulty, particularly in assessment, remain unclear. This paper presents a multiple-choice test instrument for assessing individuals' knowledge of fundamental…

A deep understanding of organic chemistry requires a learner to understand many concepts and have fluency with multiple skills. This understanding is particularly necessary for constructing and using mechanisms to explain chemical reactions. Electrophilicity and nucleophilicity are two fundamental concepts to learning and understanding reaction…

Problem solving is a key component of authentic scientific research and practice in organic chemistry. One factor that has been shown to have a major role in successful problem solving in a variety of disciplines is metacognitive regulation, defined as the control of one's thought processes through the use of planning, monitoring, and evaluation…

Reaction mechanisms are central to organic chemistry and organic chemistry education. Assessing understanding of reaction mechanisms can be evaluated holistically, wherein the entire mechanism is considered; however, we assert that such an evaluation does not account for how learners variably understand mechanistic components (e.g., nucleophile,…

A cornerstone activity in undergraduate organic laboratories revolves around students running instrumental analysis on their products and interpreting their spectra. They are left to link the theory they have learned in lecture to practical spectral interpretation. Students often memorize benchmark interpretations of peaks, such as the broad…

Scaffolds can be seen as a suitable tool to support students' learning chemistry. Digital task navigators, written scaffolds that support students in solving tasks in organic chemistry, were developed, used, and evaluated for this study. A paper task navigator was further developed into a digital task navigator, which included links to…

A multistep synthesis of a metal-free organic dye-sensitizer for solar cells was developed as a multifaceted research project for upper-division undergraduate students with a goal of introducing students to the application of organic synthesis in material science, and renewable energy research. The characterization of the dye is done by thin-layer…

In recent years, course-based undergraduate research experiences (CUREs) have been increasing in popularity as replacements for or adjuvants to the traditional laboratory experience. This approach shifts the focus from an exercise-based curriculum to an experiment-based curriculum and provides students with a more authentic and higher-impact…

A new organic chemistry experiment aimed to separate the chlorophyll precursor in plant seeds by column chromatography is described. The primary pedagogical goal in developing this experiment is to establish a simple and interesting chromatographic separation to demonstrate basic concepts and the standard procedure for this important lab…

Organic reaction mechanisms lie at the heart of developing an understanding of how the molecular world functions. However, many students simply try to memorize mechanisms, or use their knowledge of the reagent and product to create a mechanism that "works". This is not helped by the content-heavy organic chemistry curriculum which…

There has been extensive work within chemistry education research to characterize organic chemistry students' engagement in key science practices like "constructing explanations" and "engaging in argument from evidence". Less has been done to consider how organic chemistry students interact with empirical data, outside of…

In this laboratory teaching experiment, commercial cannabis oils were analyzed by undergraduate organic chemistry students using gas chromatography-mass spectrometry (GC-MS) to investigate three isomeric cannabinoids commonly found in cannabis products: cannabidiol (CBD), [delta][superscript 9]-tetrahydrocannabinol ([delta][superscript 9]-THC),…

This study aimed to analyze second-semester organic chemistry students' problem-solving strategies, specifically focusing on the resources activated while solving problems on E2, E1, and E1cB elimination reactions. Using the theoretical framework by Elby and Hammer, we defined a resource as a unit of information used in the problem-solving…

The American Chemical Society advocates a shift from rule-based to risk-based safety education for chemistry graduates, emphasizing meaningful student engagement in the risk assessment process for laboratory work. To implement this paradigm shift, we introduced RAMP (Recognize Hazards, Assess Risk, Minimize Risk, and Prevent Emergencies)-based…

A laboratory experiment was designed to introduce the practical application of biocatalysis in Bachelor and Master courses in biotechnology and medicinal chemistry, respectively. To this aim, the lipase from "Candida rugosa" was characterized (protein concentration and activity), immobilized on a carrier (by hydrophobic adsorption), and…