Advocate Aurora Research Institute (AARI) has implemented a Research Authorization and Protocol Review (RAPR) process to streamline the review and authorization of research conducted within Advocate Health (AH) Midwest. RAPR aims to facilitate the submission and review of various types of research, coordinates scientific and administrative reviews, ensures proposals are compliant with AH policies and procedures, and, when applicable, authorizes research support services to studies that are meritorious as well as operationally and financially feasible. The process uses a Research Electronic Data Capture (REDCap) platform for submission, review, scoring, and tracking of clinical research requests. Unique REDCap workflows were customized for Academic Research, Graduate Medical Education Research, Nursing Research, and Sponsored Clinical Trials. Research studies are reviewed by scientific and clinical experts, as well as research administrators, and are evaluated based on standard scoring criteria, including organizational priority, patient impact, qualifications of the study team, funding, resource availability, research quality, contracting/legal support, and cybersecurity considerations. RAPR determinations are communicated to the study team and key personnel through REDCap notifications. RAPR authorization is a mandatory requirement at AH Midwest and a prerequisite for submitting a research study to the Institutional Review Board.