Purpose: Attention is proposed to consist of three discrete neurofunctional networks, though evidence suggests that two of these -- the alerting and cognitive control networks -- are interdependent. The neural mechanism(s) underlying this interdependence have not been identified; however, the locus coeruleus -- norepinephrine (LC-NE) system may…

Objective: Experiences of "auditory hyper-reactivity" and decreased sound tolerance, which can be separated into phenotypes such as hyperacusis and misophonia, are prevalent in autism and ADHD and impact quality of life and wellbeing. Furthermore, atypical patterns of attention regulations--including hyper-focus and inattention--are…

Objectives: Although extensive research has documented associations between Attention-Deficit/Hyperactivity Disorder (ADHD) and differences in resting-state electroencephalography (EEG) oscillatory activity, the causal nature of these relationships remains uncertain. This study aimed to determine whether there is a causal relationship between…

Autism Spectrum Disorder (ASD) and Attention-Deficit/Hyperactivity Disorder (ADHD) are associated with adaptive function impairments. This study measured adaptive functioning in a sample of 92 children with ASD, including 80 children with co-occurring ADHD. Regression models examined whether ASD and ADHD symptom severity were associated with…

This systematic review and synthesis summarizes intervention research for Grade K-12 students with a reading difficulty and co-occurring inattention to identify (a) the relevant intervention literature base, (b) the student, study, and intervention characteristics of these studies, (c) the effects of these interventions on reading and behavior…

Objective: To examine the effects of triple beaded mixed amphetamine salts (TB MAS) on ADHD and executive dysfunction symptoms throughout the day in adults with DSM-5 ADHD. Method: This was a 6 week, single-blind, placebo-lead in trial of TB MAS (12.5-37.5 mg/day); all participants received 2 weeks of single-blind placebo); one individual was a…

Objective: Learning unfolds in distinct stages--acquisition, consolidation, and maintenance--shaped by cognitive mechanisms such as saliency processing, interference control, and sustained attention. ADHD in adults is associated with deficits in these cognitive processes, which in turn might lead to learning difficulties. Method: Using a novel…

Objective: Proneness to boredom has been reported in ADHD populations; however, no study to date has examined potential mediators of ADHD-related boredom. The current study investigated whether individuals with ADHD traits exhibit higher levels of boredom propensity relative to their peers without ADHD traits and explore if attention control and…

Background: Good screening tools can be of immense value in educational counselling for adults. We report two studies where we explored the factor structure and discriminative power of the Adult Reading Questionnaire (ARQ) in different samples of young adults at risk for reading impairments. Method: The ARQ was designed to screen for literacy…

Objective: The objective was to determine the differential validity of a cognitive disengagement syndrome-only (CDS-only) group from ADHD-inattentive presentation-only (IN-only), ADHD-hyperactive-impulsive presentation-only (HI-only), and ADHD-combined presentation (C-only) groups within childhood (ages 5-10) and adolescence (ages 11-16). Methods:…

A set of common-acting iron-responsive 5'untranslated region (5'UTR) motifs can fold into RNA stem loops that appear significant to the biology of cognitive declines of Parkinson's disease dementia (PDD), Lewy body dementia (LDD), and Alzheimer's disease (AD). Neurodegenerative diseases exhibit perturbations of iron homeostasis in defined brain…

To combat the ever-increasing number of symptoms of ADHD in the classroom, this article suggests a few strategies and a one-week physical activity plan for educators to adopt during the school day. These strategies are easily implemented, requiring no additional equipment, tools or extra time.

Objective: In this study, to investigate the place of T cell-mediated immunity in the etiology of ADHD, for which we do not have enough information; we aimed to investigate the activity of DPP IV and ADA, which are T cell-related enzymes, and the relationship of these enzymes with ADHD symptoms in children with ADHD. Methods: Twenty-seven children…

Objective(s): To assess the likelihood of ADHD diagnosis in children of non-US-born caregivers relative to children of US-born caregivers. Method: Cross-sectional analysis of a combined 2016 to 2019 National Survey of Children's Health dataset (n = 109,881) was performed to identify associations between caregiver's birth outside the U.S. and…

Diverse mechanisms account for the familial aggregation of certain personality traits and externalizing psychopathology. We explored the roles of positive and negative parenting as mediators of longitudinal associations between parents' maladaptive personality traits and their children's inattention/hyperactivity problems. We collected self,…