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Direct linkSugarman, Michael A.; Jacobs, Dennis R.; Paulson, Daniel; Tomlinson, M. Michele; Lichtenberg, Peter A. – Journal of Intellectual & Developmental Disability, 2014
Background: The goal of the current study was to determine if the Dementia Rating Scale-2 (DRS-2) is an appropriate tool for evaluating cognitive abilities in adults with Prader-Willi syndrome (PWS). The DRS-2 is a screening measure previously utilised in low-functioning populations with and without dementia, including individuals with…
Descriptors: Genetic Disorders, Dementia, Rating Scales, Adults
Guimond, Fanny-Alexandra; Laursen, Brett; Vitaro, Frank; Brendgen, Mara; Dionne, Ginette; Boivin, Michel – International Journal of Behavioral Development, 2016
This study used a genetically controlled design to examine the direction and the magnitude of effects in the over-time associations between perceived relationship quality with mothers and adolescent maladjustment (i.e., depressive symptoms and delinquency). A total of 163 monozygotic (MZ) twins pairs (85 female pairs, 78 male pairs) completed…
Descriptors: Genetics, Parent Child Relationship, Mothers, Path Analysis
Waite, Jane; Beck, Sarah R.; Heald, Mary; Powis, Laurie; Oliver, Chris – Journal of Autism and Developmental Disorders, 2016
Working memory (WM) impairments might amplify behavioural difference in genetic syndromes. Murine models of Rubinstein-Taybi syndrome (RTS) evidence memory impairments but there is limited research on memory in RTS. Individuals with RTS and typically developing children completed WM tasks, with participants with RTS completing an IQ assessment and…
Descriptors: Short Term Memory, Spatial Ability, Verbal Ability, Verbal Development
Davis, Beth; Murphy, M. Shaun – Teachers and Teaching: Theory and Practice, 2016
This paper inquires into the experiences of an early childhood educator named Claire who taught a young girl with a chronic illness at East Willows Elementary School, a western Canadian elementary school. Using narrative inquiry as the methodology, Claire's experiences in her curriculum making alongside Madeline a young girl with Turner syndrome…
Descriptors: Foreign Countries, Chronic Illness, Genetic Disorders, Early Childhood Education
Forbes-Lorman, Robin M.; Harris, Michelle A.; Chang, Wesley S.; Dent, Erik W.; Nordheim, Erik V.; Franzen, Margaret A. – Biochemistry and Molecular Biology Education, 2016
Understanding how basic structural units influence function is identified as a foundational/core concept for undergraduate biological and biochemical literacy. It is essential for students to understand this concept at all size scales, but it is often more difficult for students to understand structure-function relationships at the molecular…
Descriptors: Gender Differences, Models, Genetics, Undergraduate Students
Hargadon, Kristian M. – Biochemistry and Molecular Biology Education, 2016
The flow of genetic information from DNA to RNA to protein, otherwise known as the "central dogma" of biology, is one of the most basic and overarching concepts in the biological sciences. Nevertheless, numerous studies have reported student misconceptions at the undergraduate level of this fundamental process of gene expression. This…
Descriptors: Genetics, Models, Teaching Models, Teaching Methods
Selvarajah, Geeta; Selvarajah, Susila – Biochemistry and Molecular Biology Education, 2016
Students frequently expressed difficulty in understanding the molecular mechanisms involved in chromosomal recombination. Therefore, we explored alternative methods for presenting the two concepts of the double-strand break model: Holliday junction and heteroduplex formation, and Holliday junction resolution. In addition to a lecture and…
Descriptors: Genetics, Molecular Structure, Scientific Concepts, Models
Green Snyder, LeeAnne; D'Angelo, Debra; Chen, Qixuan; Bernier, Raphael; Goin-Kochel, Robin P.; Wallace, Arianne Stevens; Gerdts, Jennifer; Kanne, Stephen; Berry, Leandra; Blaskey, Lisa; Kuschner, Emily; Roberts, Timothy; Sherr, Elliot; Martin, Christa L.; Ledbetter, David H.; Spiro, John E.; Chung, Wendy K.; Hanson, Ellen – Journal of Autism and Developmental Disorders, 2016
The 16p11.2 duplication (BP4-BP5) is associated with Autism Spectrum Disorder (ASD), although significant heterogeneity exists. Quantitative ASD, behavioral and neuropsychological measures and DSM-IV diagnoses in child and adult carriers were compared with familial non-carrier controls, and to published results from deletion carriers. The 16p11.2…
Descriptors: Pervasive Developmental Disorders, Developmental Disabilities, Psychiatry, Statistical Analysis
Prevost, Luanna B.; Smith, Michelle K.; Knight, Jennifer K. – CBE - Life Sciences Education, 2016
Previous work has shown that students have persistent difficulties in understanding how central dogma processes can be affected by a stop codon mutation. To explore these difficulties, we modified two multiple-choice questions from the Genetics Concept Assessment into three open-ended questions that asked students to write about how a stop codon…
Descriptors: Science Instruction, Genetics, Scientific Concepts, Scoring
Thomas, Michael S. C.; Davis, Rachael; Karmiloff-Smith, Annette; Knowland, Victoria C. P.; Charman, Tony – Developmental Science, 2016
This article outlines the "over-pruning hypothesis" of autism. The hypothesis originates in a neurocomputational model of the regressive sub-type (Thomas, Knowland & Karmiloff-Smith, 2011a, 2011b). Here we develop a more general version of the over-pruning hypothesis to address heterogeneity in the timing of manifestation of ASD,…
Descriptors: Autism, Pervasive Developmental Disorders, Computer Simulation, Symptoms (Individual Disorders)
Patricia J. Friedrichsen; Troy D. Sadler; Kerri Graham; Pamela Brown – International Journal of Designs for Learning, 2016
In this design case, we describe our work to design and develop a socio-scientific issue (SSI) based unit of instruction for use in high school biology. Our team includes university based science educators, an experienced classroom teacher, and a microbiologist. The unit focuses on antibiotic resistant bacteria as a context for student exploration…
Descriptors: Science and Society, Secondary School Science, Science Instruction, Instructional Design
Tosto, Maria G.; Hayiou-Thomas, Marianna E.; Harlaar, Nicole; Prom-Wormley, Elizabeth; Dale, Philip S.; Plomin, Robert – Developmental Psychology, 2017
This study examines the genetic and environmental etiology underlying the development of oral language and reading skills, and the relationship between them, over a long period of developmental time spanning middle childhood and adolescence. It focuses particularly on the differential relationship between language and two different aspects of…
Descriptors: Twins, Genetics, Reading Fluency, Structural Equation Models
Munn, Maureen; Knuth, Randy; Van Horne, Katie; Shouse, Andrew W.; Levias, Sheldon – CBE - Life Sciences Education, 2017
This study examines how two kinds of authentic research experiences related to smoking behavior--genotyping human DNA (wet lab) and using a database to test hypotheses about factors that affect smoking behavior (dry lab)--influence students' perceptions and understanding of scientific research and related science concepts. The study used pre and…
Descriptors: Science Laboratories, Smoking, Genetics, Hypothesis Testing
Selzam, Saskia; Dale, Philip S.; Wagner, Richard K.; DeFries, John C.; Cederlöf, Martin; O'Reilly, Paul F.; Krapohl, Eva; Plomin, Robert – Scientific Studies of Reading, 2017
It is now possible to create individual-specific genetic scores, called genome-wide polygenic scores (GPS). We used a GPS for years of education ("EduYears") to predict reading performance assessed at UK National Curriculum Key Stages 1 (age 7), 2 (age 12) and 3 (age 14) and on reading tests administered at ages 7 and 12 in a UK sample…
Descriptors: Genetics, Biological Sciences, Scores, Prediction
Stern, Florian; Kampourakis, Kostas – Studies in Science Education, 2017
Research in genetics and genomics is advancing at a fast pace, and thus keeping up with the most recent findings and conclusions can be very challenging. At the same time these recent findings and conclusions have made necessary a reconceptualization of genes and heredity, both in science and in science education, beyond the mostly gene-centred…
Descriptors: Genetics, Literacy, Science Instruction, Teaching Methods
