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Peer reviewed
Direct linkLoo, Joanne C. Y.; Boot, Erik; Corral, Maria; Bassett, Anne S. – Journal of Applied Research in Intellectual Disabilities, 2020
Background: Many individuals with intellectual disabilities and their caregivers struggle to provide accurate and complete information to healthcare providers. Method: The present authors provided personal medical information cards (PMICs) containing contact and medical information to 52 Canadian adults with 22q11.2 deletion syndrome, a genetic…
Descriptors: Adults, Congenital Impairments, Genetic Disorders, Intellectual Disability
Brown, Grant R.; Dagen, Claire; O'Donnell, Ben Reilly; Graves, Jeff A. – Journal of Biological Education, 2020
We provide a protocol for rapid DNA extraction from spiders suitable for undergraduate practical sessions. Students who were previously naïve to the theory and laboratory technique of DNA barcoding were successfully able to extract and recover 29 DNA sequences from 16 species of small spiders in the family Linyphiidae. We anticipate that with…
Descriptors: Teaching Methods, Biology, Science Instruction, Genetics
Venkatesh, Ishwariya; Makky, Khadijah – American Biology Teacher, 2020
The field of epigenetics is progressing rapidly and becoming indispensable to the study of fundamental gene regulation. Recent advances are redefining our understanding of core components that regulate gene expression during development and in human diseases. Scientific knowledge on the importance of epigenetic regulation is now well known and…
Descriptors: Science Instruction, Teaching Methods, Genetics, Science Education
Heuer, Sarah E.; Neuner, Sarah M.; Hadad, Niran; O'Connell, Kristen M. S.; Williams, Robert W.; Philip, Vivek M.; Gaiteri, Chris; Kaczorowski, Catherine C. – Learning & Memory, 2020
Individual differences in cognitive decline during normal aging and Alzheimer's disease (AD) are common, but the molecular mechanisms underlying these distinct outcomes are not fully understood. We utilized a combination of genetic, molecular, and behavioral data from a mouse population designed to model human variation in cognitive outcomes to…
Descriptors: Cognitive Processes, Resilience (Psychology), Alzheimers Disease, Genetics
Reiss, Michael J. – School Science Review, 2020
School genetics is changing. Nowadays, students are more likely to be introduced to the idea that many characteristics of organisms, including those of humans, are not determined by the actions of just one or two genes but result from interactions between the products of many genes and the environments of each organism. This article asks whether…
Descriptors: Science Instruction, Genetics, Intelligence, Outcomes of Education
Overbeek, Geertjan; Creasey, Nicole; Wesarg, Christiane; Huijzer-Engbrenghof, Marijke; Spencer, Hannah – New Directions for Child and Adolescent Development, 2020
Child maltreatment is a global phenomenon that affects the lives of millions of children. Worldwide, as many as one in three to six children encounter physical, sexual, or emotional abuse from their caregivers. Children who experience abuse often show alterations in stress reactivity. Although this alteration may reflect a physiological survival…
Descriptors: Child Abuse, Genetics, Stress Variables, Child Behavior
Haskel-Ittah, Michal; Duncan, Ravit Golan; Yarden, Anat – CBE - Life Sciences Education, 2020
The idea of the interaction between genes and environment in the formation of traits is an important component of genetic literacy, because it explains the plastic nature of phenotypes. However, most studies in genetics education characterize challenges in understanding and reasoning about genetic phenomena that do not involve modulation by the…
Descriptors: Science Instruction, Genetics, College Science, Undergraduate Students
Waito, Ashley A.; Plowman, Emily K.; Barbon, Carly E. A.; Peladeau-Pigeon, Melanie; Tabor-Gray, Lauren; Magennis, Kelby; Robison, Raele; Steele, Catriona M. – Journal of Speech, Language, and Hearing Research, 2020
Purpose: To date, research characterizing swallowing changes in individuals with amyotrophic lateral sclerosis (ALS) has primarily relied on subjective descriptions. Thus, the degree to which swallowing physiology is altered in ALS, and relationships between such alterations and swallow safety and/or efficiency are not well characterized. This…
Descriptors: Human Body, Genetic Disorders, Physiology, Psychomotor Skills
Ethridge, Lauren; Thaliath, Andrew; Kraff, Jeremy; Nijhawan, Karan; Berry-Kravis, Elizabeth – American Journal on Intellectual and Developmental Disabilities, 2020
Auditory processing abnormalities in fragile X syndrome (FXS) may contribute to difficulties with language development, pattern identification, and contextual updating. Participants with FXS (N = 41) and controls (N = 27) underwent auditory event-related potentials during presentation of an oddball paradigm. Data was adequate for analysis for 33…
Descriptors: Auditory Perception, Cognitive Processes, Neurological Impairments, Genetic Disorders
Mansolf, Maxwell; Vreeker, Annabel; Reise, Steven P.; Freimer, Nelson B.; Glahn, David C.; Gur, Raquel E.; Moore, Tyler M.; Pato, Carlos N.; Pato, Michele T.; Palotie, Aarno; Holm, Minna; Suvisaari, Jaana; Partonen, Timo; Kieseppä, Tuula; Paunio, Tiina; Boks, Marco; Kahn, René; Ophoff, Roel A.; Bearden, Carrie E.; Loohuis, Loes Olde; Teshiba, Terri; deGeorge, Daniella; Bilder, Robert M. – Educational and Psychological Measurement, 2020
Large-scale studies spanning diverse project sites, populations, languages, and measurements are increasingly important to relate psychological to biological variables. National and international consortia already are collecting and executing mega-analyses on aggregated data from individuals, with different measures on each person. In this…
Descriptors: Item Response Theory, Data Analysis, Measurement, Validity
Perreault, Melanie; Haibach-Beach, Pamela; Lieberman, Lauren; Foster, Elizabeth – Journal of Visual Impairment & Blindness, 2020
Introduction: Children with CHARGE syndrome often show delays in balance and motor skills due to multisensory impairments. Research also suggests that children with CHARGE syndrome have fewer opportunities to engage in physical activity. However, little research has examined the relationship among all of these variables. Thus, the purpose of this…
Descriptors: Psychomotor Skills, Genetic Disorders, Children, Adolescents
Cook, Ian A.; Wilson, Andrew C.; Peters, Jurriaan M.; Goyal, Monisha N.; Bebin, E. Martina; Northrup, Hope; Krueger, Darcy; Leuchter, Andrew F.; Sahin, Mustafa – Journal of Autism and Developmental Disorders, 2020
Tuberous sclerosis complex (TSC) is a multisystem disorder with increased prevalence of autism spectrum disorders (ASDs). This project aimed to characterize the autism phenotype of TSC and identify biomarkers of risk for ASD. Because abnormalities of EEG during sleep are tied to neurodevelopment in children, we compared electroencephalographic…
Descriptors: Diagnostic Tests, Sleep, Autism, Pervasive Developmental Disorders
Fielding-Gebhardt, Heather; Warren, Steven F.; Brady, Nancy C. – Journal of Autism and Developmental Disorders, 2020
Parenting children with neurodevelopmental disabilities is often challenging. Biological mothers of children with Fragile X Syndrome (FXS) may be susceptible to increased risk of mental health problems. This study examined the longitudinal relationships between maternal mental health, child challenging behaviors, and mother-child relationship…
Descriptors: Mothers, Mental Health, Child Behavior, Behavior Problems
Peffer, Melanie E.; Renken, Maggie; Enderle, Patrick; Cohen, Jonathan – Research in Science Education, 2021
Young children can struggle to learn difficult disciplinary content and important skills for practicing science. Problem-based learning (PBL) may be useful for addressing such difficulties, yet evidence to support its usefulness in elementary school-aged children is limited. We considered the role of a PBL unit in improving students' genetics…
Descriptors: Problem Based Learning, Elementary School Students, Difficulty Level, Genetics
Srivastava, Siddharth; Clark, Bennett; Landy-Schmitt, Colleen; Offermann, Elizabeth A.; Kline, Antonie D.; Wilkinson, Samuel T.; Grados, Marco A. – Journal of Autism and Developmental Disorders, 2021
Cornelia de Lange syndrome (CdLS) is associated with repetitive and self-injurious behaviors (RBs, SIB). Evaluating children with CdLS, this study: (1) characterizes the spectrum of RBs; (2) characterizes the impact and severity of RBs including SIB; (3) describes how age and adaptive functioning relate to RBs including SIB. Fifty children…
Descriptors: Behavior Problems, Self Destructive Behavior, Genetic Disorders, Intellectual Disability
