Intercultural mentoring relationships, which are increasing in higher education, require cultural competence to be effective and successful. Therefore, the current study focused on perceptions of cultural competence and intercultural mentoring effectiveness among graduate students and faculty in departments of Agricultural Leadership, Communication, Education, and Extension (ALCEE) and leadership educators in the United States. Using an online survey, 32 participants shared their perceptions of mentoring effectiveness and cultural competence. The findings from the thematic analysis revealed a perception of intercultural mentoring as aiding the development of cultural competence by providing an experiential learning platform where participants learned intercultural relationship skills (e.g., how to deal with cultural differences). In addition, lessons learned through intercultural mentoring were perceived as transferable to other intercultural relationships. Our findings inform specific recommendations for intercultural mentoring training.