Interventions for drug abuse and other maladaptive habitual behaviors may yield temporary success but are often fragile and relapse is common. This implies that current interventions do not erase or substantially modify the representations that support the underlying addictive behavior--that is, they do not cause true unlearning. One example of an…

Models of differential susceptibility hypothesize that neural function may be a marker of differential susceptibility to context, but no studies have tested this hypothesis. Using a sample of 310 young men from low-income urban neighborhoods, this study investigated amygdala reactivity to facial expressions as a moderator of the relations between…

This study is about artificial neural network modeling of the linguistic challenges encountered by students learning Turkish as a foreign language in universities in France. The study was conducted in four universities where Turkish is taught as an optional foreign language. Sixty-six students whose mother tongues were either Arabic or French…

A key index of top-down control in task switching--preparation for a switch--is underexplored in language switching. The well-documented EEG "signature" of preparation for a task switch--a protracted positive-polarity modulation over the posterior scalp--has thus far not been reported in language switching, and the interpretation of…

We investigated the extent to which the literal meanings of the words forming literally plausible idioms (e.g., "break the ice") are semantically composed and how the idiomatic meaning is integrated in the unfolding sentence representation. Participants read ambiguous idiom strings embedded in highly predictable, literal, and idiomatic…

Brain damaged participants offer an opportunity to evaluate the cognitive and linguistic processes and make assumptions about how the brain works. Cognitive linguists have been investigating the underlying mechanisms of idiom comprehension to unravel the ongoing debate on hemispheric specialization in figurative language comprehension. The aim of…

The question of "how we learn" continues to direct scholarly debate, yet undergraduate teaching is typically designed to homogenise the learning environment. This is despite heterogeneous learning outcomes ensuing for students, owing to their different learning styles. Accordingly, we examine the relationship between teaching…

Creativity allows to see things in a new way--to go beyond the information given, recombining, thinking in unconventional ways, using little known or neglected means. To be clinical, it starts in the frontal lobe, that part of the brain which has the boundless capacity to dream up things. Feeding one's creativity both in the classroom and away…

a-calcium/calmodulin-dependent protein kinase (aCaMKII) T286-autophosphorylation provides a short-term molecular memory that was thought to be required for LTP and for learning and memory. However, it has been shown that learning can occur in aCaMKII-T286A mutant mice after a massed training protocol. This raises the question of whether there…

An important cellular mechanism contributing to the strength and duration of memories is activity-dependent alterations in the strength of synaptic connections within the neural circuit encoding the memory. Reversal of the memory is typically correlated with a reversal of the cellular changes to levels expressed prior to the stimulation. Thus, for…

It has been more than 50 years since the first description of ocular dominance plasticity--the profound modification of primary visual cortex (V1) following temporary monocular deprivation. This discovery immediately attracted the intense interest of neurobiologists focused on the general question of how experience and deprivation modify the brain…

Although significant advances have been made in our understanding of the neural basis of learning and memory over the past hundred years, the translation of these neuroscientific insights into classroom teaching practice has been very limited. In this review, we discuss the historical development of pedagogy, cognitive psychology, and the…

The medial prefrontal cortex (mPFC) and the right temporo-parietal junction (rTPj) are highly involved in social understanding, a core area of impairment in autism spectrum disorder (ASD). We used fMRI to investigate sex differences in the neural correlates of social understanding in 27 high-functioning adults with ASD and 23 matched controls.…

Autism spectrum disorder (ASD) is characterized by atypical visual perception both in the social and nonsocial domain. In order to measure a reliable visual response, visual evoked potentials were recorded during a passive pattern-reversal stimulation in adolescents and adults with and without ASD. While the present results show the same…

Mathematical disabilities (MD) have a negative life-long impact on professional success, employment, and health outcomes. Yet little is known about the intrinsic functional brain organization that contributes to poor math skills in affected children. It is now increasingly recognized that math cognition requires coordinated interaction within a…