An undergraduate biochemistry laboratory experiment is described that utilizes free online bioinformatics tools along with readily available exonucleases to study the effects of base stacking and hydrogen bonding on the UV absorbance of DNA samples. UV absorbance of double-stranded DNA at the ?[subscript max] is decreased when the DNA bases are…

Refractive error is a common social issue in every walks of human life, and its prevalence recorded the highest among Chinese population, particularly among people living in southern China, Hong Kong, Thailand, Singapore, and Malaysia. Refractive error is the simplest disorder to treat and supposed to cost the effective health care intervention.…

Transition metals play an important role in many biological processes, however, they are also toxic at high concentrations. Therefore, the uptake and efflux of these metals must be tightly regulated by the cell. Bacteria have evolved a variety of pathways and regulatory systems to monitor the presence and concentration of metals in the cellular…

The emerging field of molecular epigenetics studies relatively stable changes in genetic activity that are not due to changes in the DNA sequence. Initial research results indicate a functional role for epigenetic mechanisms in neuron development and neuronal cell function. However, concepts that integrate these findings in an overall theory of…

While it appears in some quarters that epigenetics is a new approach in science, it is a phenomenon discussed even by Aristotle. An epigenetic approach holds that all response systems are synthesized during ontogeny and that this synthesis involves the integrative influence of both intraorganic processes and extrinsic stimulative conditions. It…

Technological and methodological advances, in particular next-generation sequencing and chromatin profiling, has led to a deluge of data on epigenetic mechanisms and processes. Epigenetic regulation in the brain is no exception. In this commentary, Ehud Lamm writes that extending existing frameworks for thinking about psychological development to…

Natural selection is one of the most important topics in biology and it helps to clarify the variety and complexity of organisms. However, students in almost every stage of education find it difficult to understand the mechanism of natural selection and they can develop misconceptions about it. This article provides an active model of natural…

One of the challenges humans face is making collective decisions with regards to controversial issues related to science, namely socio-scientific issues (SSIs). Genetic modification, nuclear energy, experimental drugs, 5G technology are a few examples of SSIs. Some of the concerns posed by such issues are compromise to privacy and identity, threat…

History of science (HOS) plays a substantial role in the enhancement of rooted understanding in science teaching and learning. HOS of evolution and genetics has not been included in Vietnamese biology textbooks. This study aims to investigate the necessity of introducing evolution and genetics HOS into Vietnamese textbooks. A case study approach…

Maternal smoking during pregnancy (SDP) has been linked to poorer offspring executive function across development, but SDP does not occur independent of other familial risk factors. As such, poor and inconsistent control for potential confounds, notably shared familial (i.e., genetic and environmental) confounds, preclude concluding causal effects…

Schools in Australia are required to promote equitable access to education and provide support services to students with chronic health conditions (CHCs). This qualitative study was conducted to explore stakeholders' experiences and perceptions regarding school-based support. In-depth interviews were conducted with 38 parents of upper secondary…

This study aimed to examine the relative effectiveness of using an animation versus static pictures in terms of supporting the learning of genetics. To provide a methodologically sound comparison, the two sessions were constructed to be equivalent and were designed based on principles provided by the cognitive theory of multimedia learning and the…

We developed a method for using Coh-Metrix to automatically analyze tutorial dialogues. Coh-Metrix, a web-based tool for automatically evaluating text, is freely available to researchers. We applied the method to 190 tutorial dialogues between women and "BRCA Gist" from two experiments. "BRCA Gist" is an intelligent tutoring…

This study investigated whether brain-derived neurotrophic factor (BDNF) genotype moderated inhibitory control during an emotionally valenced task in a sample of internationally adopted adolescents (N = 109, ages 12-13 years) who spent their early years in institutional care. Participants were genotyped for the Val66Met polymorphism of the BDNF…

The standard model of the role of early experience in human development assumes that children's environments in their first years of life are dominant influences on who they become as adults. The standard model favors interventions to improve children's long-term outcomes that start early in life and are intensive in time and attention from…