The [delta] subunit of the GABA[subscript [Alpha]] receptor (GABA[subscript [Alpha]]R) is highly expressed in the dentate gyrus of the hippocampus. Genetic deletion of this subunit reduces synaptic and extrasynaptic inhibition and decreases sensitivity to neurosteroids. This paper examines the effect of these changes on hippocampus-dependent trace…

After training conditional discriminations among selected stimuli from two perceptual classes, the emergence of novel relations involving other members of both classes was assessed using cross-class probes. The cross-class probes were presented using one of four different testing schedules. In the 2/9 test, nine different probes were presented in…

This military-developed text consists of three blocks of instructional materials for use by those studying to become refrigeration and air conditioning specialists. Covered in the individual course blocks are the following topics: refrigeration and trouble analysis, thermodynamics, and principles of refrigeration; major components and domestic and…

This plan of instruction, study guides, workbooks, and programmed texts for a secondary-postsecondary-level course in refrigeration and air conditioning are one of a number of military-developed curriculum packages selected for adaptation to vocational instruction and curriculum development in a civilian setting. It is the first section of a…

In this study the assumption was tested experimentally, whether prompting for reflection will enhance hypermedia learning and transfer. Students of the experimental group were prompted at each navigation step in a hypermedia system to say the reasons why they chose this specific information node out loud whereas the students of the control group…

Stress facilitates memory formation, but only when the stressor is closely linked to the learning context. These effects are, at least in part, mediated by corticosteroid hormones. Here we demonstrate that corticosterone rapidly facilitates synaptic potentiation in the mouse hippocampal CA1 area when high levels of the hormone and high-frequency…

Understanding the function of the distinct amygdaloid nuclei in learning comprises a major challenge. In the two studies described herein, we used c-Fos immunolabeling to compare the engagement of various nuclei of the amygdala in appetitive and aversive instrumental training procedures. In the first experiment, rats that had already acquired a…

Adaptive motor actions require prior knowledge of instrumental contingencies. With practice, these actions can become highly automatic in nature. However, the molecular and anatomical substrates mediating these related forms of learning are not understood. In the present study, we used in situ hybridization to measure the mRNA levels of two…

We have used a genetically tractable model system, the fruit fly "Drosophila melanogaster" to study the interdependence between sensory processing and associative processing on learning performance. We investigated the influence of variations in the physical and predictive properties of color stimuli in several different operant-conditioning…

Provides an overview of the current methods of behavior modification, reviews some critical issues, such as fear of control, use of aversive control, and behavior modification in prisons, in an effort to aid in differentiating warranted from unwarranted concerns. Ethical standards and practices are discussed. (Author/AM)

Thirty college students and 30 moderately retarded persons averaging approximately equal age received eight alternating phases of acquisition and extinction trials with an electric pulse as the unconditioned stimulus for classical eyelid conditioning. (Author)

This study investigates the efficacy of symbolic modeling and role-playing therapy in the reduction of avoidance behaviors. After treatment, role-playing subjects demonstrated significantly less avoidance behavior and lower subjective fear ratings than the modeling or control group subjects. (Author/SJL)

The long-term treatment program and follow-up of a case of chronic, severe, multiple self-injurious behavior is presented. Contingent electric shock and differential reinforcement of other behavior were the primary techniques utilized. Total suppression was achieved in the laboratory setting, but extending control to the natural environment proved…

In a two part article the author first discusses the importance of fluency, rate, breathstream management, prosody, and self-confidence to the replacement of stuttering with normal speech; and second outlines specific clinical procedures for achieving these goals with adult and adolescent stutterers. (Author/LS)

Examined was the effect of operant-conditioning on the pica behavior (eating inedible substances) of a 14-year-old severely retarded institutionalized boy. (CL)