In the second half of the eighteenth century, intellectuals, stimulated by the sensualist theories of Etienne-Bonnot de Condillac (1714?80) and John Locke (1632?1704), tried to understand how a sensorially disabled person, such as one suffering from deafness or blindness was able to reason and develop ideas, for the senses were thought to be the…

This article describes a CPR training course modified for a student with cerebral palsy. Brian is a 10th grade student with cerebral palsy affecting his right side. Brian had a difficult time in the class and was not able to meet the standards required to pass his CPR training. Here, the author discusses how two adaptations were utilized, that…

Brain research opens new frontiers in working with children and youth experiencing conflict in school and community. Blending this knowledge with resilience science offers a roadmap for reclaiming those identified as "at risk." This article applies findings from resilience research and recent brain research to identify strategies for reaching…

Previous research with both brain-damaged and neurologically intact populations has demonstrated that the right cerebral hemisphere (RH) is superior to the left cerebral hemisphere (LH) at detecting anomalies (or incongruities) in objects (Ramachandran, 1995; Smith, Tays, Dixon, & Bulman-Fleming, 2002). The current research assesses whether the RH…

An emerging body of literature points to the prominent role of the frontal lobes in the retrieval of verbs, whereas production of common and proper nouns arguably is mediated primarily by posterior and anterior temporal regions, respectively. Although the majority of studies examining the neuroanatomic distinctions between verb and noun retrieval…

Two findings serve as the hallmark for hemispheric specialization during lateralized lexical decision. First is an overall word advantage, with words being recognized more quickly and accurately than non-words (the effect being stronger in response latency). Second, a right visual field advantage is observed for words, with little or no…

A traditional method of localizing brain functions has been to identify shared areas of brain damage in individuals who have a particular deficit. The rationale of this "lesion overlap" approach is straightforward: if the individuals can no longer perform the function, the area of brain damaged in most of these individuals must have been…

Using 12 participants we conducted an fMRI study involving two tasks, word reversal and rhyme judgment, based on pairs of natural speech stimuli, to study the neural correlates of manipulating auditory imagery under taxing conditions. Both tasks engaged the left anterior superior temporal gyrus, reflecting previously established perceptual…

Aversive conditioning is an ideal model for studying cholinergic effects on the processes of learning and memory for several reasons. First, deficits produced by selective lesions of the anatomical structures shown to be critical for Pavlovian fear conditioning and inhibitory avoidance (such as the amygdala and hippocampus) resemble those deficits…

False memories are often demonstrated using the misinformation paradigm, in which a person's recollection of a witnessed event is altered after exposure to misinformation about the event. The neural basis of this phenomenon, however, remains unknown. The authors used fMRI to investigate encoding processes during the viewing of an event and…

Deletions, translocations, or point mutations in the CREB-binding protein (CBP) gene have been associated with Rubinstein-Taybi Syndrome; a human developmental disorder characterized by retarded growth and reduced mental function. To examine the role of CBP in memory, transgenic mice were generated in which the CaMKII[alpha] promoter drives…

Information storage in the brain is a temporally graded process involving different memory phases as well as different structures in the mammalian brain. Cortical plasticity seems to be essential to store stable long-term memories, although little information is available at the moment regarding molecular and cellular events supporting memory…

Developmental Science aims to generate a new body of knowledge that encompasses and integrates findings from various well-defined academic disciplines concerned with developmental processes of human and non-human organisms. Although all development related research traditions surely have their own distinct history, certain theoretical ideas…

This brief summarizes the working paper, "The Science of Early Childhood Development: Closing the Gap between What We Know and What We Do" (ED503049). In early childhood, research on the biology of stress shows how major adversity, such as extreme poverty, abuse, or neglect can weaken developing brain architecture and permanently set the…

Background: Neurofeedback (NF) is a form of behavioural training aimed at developing skills for self-regulation of brain activity. Within the past decade, several NF studies have been published that tend to overcome the methodological shortcomings of earlier studies. This annotation describes the methodical basis of NF and reviews the evidence…