This laboratory experiment utilizes an exploration of the storage stability of beer to introduce basic aspects of electron-paramagnetic-resonance (EPR) spectroscopy. Radicals formed upon aerobic forced-aging of beer samples are established by using a spin-trap. The students are introduced to basic principles of EPR spectroscopy and food and…

The MicRoboCop project introduces chemistry students to the concepts and protocols of synthetic biology. MicRoboCop is a biosensor that has been designed for unique applications in forensic chemistry. The lab is carried out in collaboration with an instructor teaching a genetics course. Students in the biology course synthesize biosensors using…

Atypical functional connectivity (FC) and an imbalance of excitation-to-inhibition (E/I) have been previously reported in cerebro-cerebellar circuits in autism spectrum disorder (ASD). The current investigation used resting state fMRI and proton magnetic resonance spectroscopy ([superscript 1]H-MRS) to examine the relationships between E/I…

The value of neurocognitive measures to study memory, attention, cognition, and learning is well established. However, the vast majority of work using these tools is performed in tightly controlled lab experiments using simple lab stimuli. This article looks at the viability of using multimodal neurocognitive instruments to measure implicit…

Quantum mechanics is a notoriously difficult subject to learn, due to a lack of real-world analogies that might help provide an intuitive grasp of the underlying ideas. Discrete energy levels and absorption and emission wavelengths in atoms are sometimes described as uniquely quantum phenomena, but are actually general to spatially confined waves…

An advanced undergraduate experiment involving the synthesis and characterization of a series of six unique cinnamamides is described. This experiment allows for a progressive mastery of skills students need to tackle more complex NMR structure elucidation problems. Characterization of the products involves IR spectroscopy, GCMS, and proton,…

The use of [superscript 1]H NMR spectroscopy to analyze the number-average molecular weight of a methoxy poly(ethylene glycol) (MPEG) and an acetate derivative of this MPEG is described. These analyses illustrate NMR principles associated with the chemical shift differences of protons in different environments, NMR integration, and the effect of…

Small organic molecules offer a rich opportunity to discuss the interplay of chemical structure with properties such as the melting point and phenomena such as glass formation and can form the basis of fundamental considerations of structure-property relationships in macromolecules. Of particular importance are thermal transitions, specifically…

Previous work has noted that some children with autism spectrum disorder (ASD) display weaknesses in receptive vocabulary relative to expressive vocabulary abilities. The current study extended previous work by examining the receptive-expressive vocabulary profile in boys with idiopathic ASD and boys with concomitant ASD and fragile X syndrome…

This paper represents the second contribution from an action research study on a bachelor-level quantum chemistry and spectroscopy course. In the proposed instructional model, active learning principles are extended outside lectures to form a student-centred course structure. The new model resulted in superior learning outcomes compared to a class…

A green chemistry experiment is presented for teaching an undergraduate quantitative analysis/analytical chemistry laboratory class through the use of black tea leaf extract for the determination of iron in supplement tablets. Dried tea leaf is a safe, low cost, and widely available source of natural extract that can be used in place of more toxic…

This commentary summarizes the authors' basic disagreements with the paper, "Rabbit-Ears, VSEPR Sterics, and Other Orbital Anachronisms," which criticizes the authors' usage of the hybrid orbitals for H[subscript 2]O in their book, "A Chemist's Guide to Valence Bond Theory" (Shaik and Hiberty, 2008). The current article shows…

Bioinorganic topics are ubiquitous in the inorganic chemistry curriculum; however, experiments to enhance understanding of related topics are scarce. In this proposed laboratory, upper undergraduate students assess the biological interaction of molybdenocene dichloride (Cp2MoCl2) with bovine serum albumin (BSA) by fluorescence spectroscopy.…

This guided-inquiry, upper-division undergraduate organic lab experiment, a hybrid of problem-based learning (PBL); process-oriented, guided-inquiry learning (POGIL); and peer-led team learning (PLTL) has been developed to ease the transition from the undergraduate lab to a research lab environment. The characterization of a mixture of camphor and…

An integrated laboratory experiment applying concepts and techniques from organic chemistry, inorganic chemistry, and instrumental analysis is presented for use in the undergraduate curriculum. This experiment highlights the synthesis, characterization, and use of tris(2-pyridylmethyl)amine (TPMA) to make complexes with different metal salts. It…