We studied the correlation between response to fluvoxamine and serotonin transporter gene promoter region polymorphism (5-HTTLPR). Eighteen children with autistic disorder completed a 12-week double-blind, placebo-controlled, randomized crossover study of fluvoxamine. Behavioral assessments were obtained before and at 12 weeks of treatment.…

The purpose of this study was to identify common and domain-specific cognitive characteristics of gifted students based on an integrated model of human abilities. This study is based on the premise that abilities identified by tests can appear as observable characteristics in test or school situations. Abilities proposed by major models of…

Studies of gene expression following fear conditioning have demonstrated that the inducible transcription factor, "egr-1," is increased in the lateral nucleus of the amygdala shortly following fear conditioning. These studies suggest that "egr-1" and its protein product Egr-1 in the amygdala are important for learning and memory of fear. To…

Each of the elements required to create a healthy baby--genetics, the anatomy of the male and female reproductive system, the processes by which eggs and sperm are produced, the processes by which the embryo is created and implanted, maternal health during pregnancy, and embryonic/fetal growth and development--is vulnerable to damage by…

Biomonitoring is a public health tool that has been used by scientists and researchers for decades to test blood, bone, urine, hair, human milk, adipose tissue, and other body substances for the presence of toxic chemicals, in order to assess what is called the "chemical body burden." Biomonitoring helps to: (1) identify which chemicals…

A technique to study combined influence of environmental and genetic factors on the base of changes in phenotype distributions is presented. Histograms are exploited as base analyzed characteristics. A continuous time, discrete state Markov process with piece-wise constant interstate transition rates is associated with evolution of each histogram.…

During three series of molecular genetics experiments, our students engage in ungraded discussions of research articles related to their experiments. The research articles are selected less for their relevance to students' laboratory experience than for their focus on experimental design and the clarity of data presentation. By discussing these…

The working drafts of the human genome, announced in February 2001, have clearly provided a breakthrough in biochemistry and molecular biology research. The scientific data also provide an opportunity to vary a typical approach to teaching. Advanced graduate students at our university can elect to take a course in molecular genetics. The human…

This paper presents the development of a 3-D virtual environment in Second Life for the delivery of standards-based science content for middle school students in the rural Appalachian region of Southeast Ohio. A mixed method approach in which quantitative results of improved student learning and qualitative observations of implementation within…

The aim of this study is to collect and evaluate opinions of CAI experts and biology teachers about a high school level Computer Assisted Biology Instruction Material presenting computer-made modelling and simulations. It is a case study. A material covering "Nucleic Acids and Protein Synthesis" topic was developed as the…

In an effort to overcome deficiencies in teaching molecular biology at school, a workshop in an out-of-school laboratory including only authentic experiments was developed. Evaluation of 337 A-level 12th graders followed a quasi-experimental design, with one hands-on group, two non-experimental control groups (at school/in the laboratory), and one…

The present work investigated cognitive, linguistic and narrative abilities in a group of children suffering from Duchenne Muscular Dystrophy, an allelic X-linked recessive disorder caused by mutations in the gene encoding dystrophin. The patients showed mildly reduced IQ with lower Verbal than Performance Intelligence Quotient and were mildly…

For the past 50 years, adults who were adopted during infancy have been research participants for empirical studies with goals ranging from twin studies for heritability, to adjustment following adoption, to attachment. While the research body is broad, it has given little attention to counseling practices with adopted adults. Because empirical…

The objectives of this study were: (1) to examine the psychometric properties of the Assessment of Life Habits (LIFE-H) for children; and (2) to draw a profile of the level of participation among children of 5 to 13 years of age with various impairments. The research team adapted the adult version of the LIFE-H in order to render it more…

The scope of this bibliography encompasses the social and psychological aspects of genetic disorders. The bibliography lists selected English-language articles and books from the professional literature along with audiovisual materials produced by both voluntary organizations and professional filmmakers. The entries are organized by the following…