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Ciernia, Annie Vogel; Kramár, Enikö A.; Matheos, Dina P.; Havekes, Robbert; Hemstedt, Thekla J.; Magnan, Christophe N.; Sakata, Keith; Tran, Ashley; Azzawi, Soraya; Lopez, Alberto; Dang, Richard; Wang, Weisheng; Trieu, Brian; Tong, Joyce; Barrett, Ruth M.; Post, Rebecca J.; Baldi, Pierre; Abel, Ted; Lynch, Gary; Wood, Marcelo A. – Learning & Memory, 2017
Recent human exome-sequencing studies have implicated polymorphic Brg1-associated factor (BAF) complexes (mammalian SWI/SNF chromatin remodeling complexes) in several intellectual disabilities and cognitive disorders, including autism. However, it remains unclear how mutations in BAF complexes result in impaired cognitive function. Post-mitotic…
Descriptors: Intellectual Disability, Autism, Genetics, Neurological Impairments
Zhang, Xu; Shao, Meng; Gao, Lu; Zhao, Yuanyuan; Sun, Zixuan; Zhou, Liping; Yan, Yongmin; Shao, Qixiang; Xu, Wenrong; Qian, Hui – Biochemistry and Molecular Biology Education, 2017
Laboratory exercise is helpful for medical students to understand the basic principles of molecular biology and to learn about the practical applications of molecular biology. We have designed a lab course on molecular biology about the determination of single nucleotide polymorphism (SNP) in human REV3 gene, the product of which is a subunit of…
Descriptors: Molecular Biology, Genetics, Medical Students, Laboratory Experiments
Long, Fiachra – Journal of Philosophy of Education, 2017
Peter Sloterdijk presented a reading of Heidegger's "Letter on Humanism" at a conference held at Elmau in 1999. Reinterpreting the meaning of humanism in the light of Heidegger's "Letter," Sloterdijk focused his presentation on the need to redefine education as a form of genetic "taming" and proposed what seemed to be…
Descriptors: Philosophy, Humanism, Genetics, Content Analysis
Kerri P. Nowell; Robin Goin-Kochel; Samuel McQuillin; Sarah S. Mire – Review Journal of Autism and Developmental Disorders, 2017
Profiles of scores on measures of intellectual functioning may aid in understanding etiology and developing targeted intervention in autism spectrum disorder (ASD) by providing details about specific phenotypes or subpopulations of ASD. Research investigating the relationship between ASD symptoms and intellectual functioning suggests that scores…
Descriptors: Autism Spectrum Disorders, Cognitive Ability, Profiles, Identification
Evan L. Ardiel; Alex J. Yu; Andrew C. Giles; Catharine H. Rankin – npj Science of Learning, 2017
Habituation is a non-associative form of learning characterized by a decremented response to repeated stimulation. It is typically framed as a process of selective attention, allowing animals to ignore irrelevant stimuli in order to free up limited cognitive resources. However, habituation can also occur to threatening and toxic stimuli,…
Descriptors: Habituation, Stimuli, Brain, Learning Processes
Dale, Philip S.; Rice, Mabel L.; Rimfeld, Kaili; Hayiou-Thomas, Marianna E. – Journal of Speech, Language, and Hearing Research, 2018
Purpose: There is a need for well-defined language phenotypes suitable for adolescents in twin studies and other large-scale research projects. Rice, Hoffman, and Wexler (2009) have developed a grammatical judgment measure as a clinical marker of language impairment, which has an extended developmental range to adolescence. Method: We conducted…
Descriptors: Language Impairments, Twins, Adolescents, Genetics
Yapici, Ibrahim Ümit; Ertas Karaaslan, Zeynep – Asia-Pacific Forum on Science Learning and Teaching, 2018
The present study aimed to evaluate the use of metaphors by preservice science teachers on the subject of genetically modified organisms (GMOs). In the study, a phenomenology method was employed in the scope of a qualitative research model. The study group was composed of 189 preservice teachers who were employed in various science fields (e.g.,…
Descriptors: Preservice Teachers, Science Teachers, Language Usage, Figurative Language
Sabatino DiCriscio, Antoinette; Troiani, Vanessa – Journal of Autism and Developmental Disorders, 2018
Atypical visual perception has increasingly been described in individuals with autism spectrum disorders (ASD) and linked to quantitative, autism-like features that are present in children and adults without ASD. We investigated whether individual differences in visual processing skills were related to quantitative measures of autism traits in a…
Descriptors: Autism, Pervasive Developmental Disorders, Genetics, Visual Perception
West, Melina J.; Copland, David A.; Arnott, Wendy L.; Nelson, Nicole L.; Angwin, Anthony J. – Journal of Autism and Developmental Disorders, 2018
The current study investigated whether those with higher levels of autism-like traits process emotional information from speech differently to those with lower levels of autism-like traits. Neurotypical adults completed the autism-spectrum quotient and an emotional priming task. Vocal primes with varied emotional prosody, semantics, or a…
Descriptors: Suprasegmentals, Semantics, Cues, Nonverbal Communication
Wise, Michael J. – Bioscene: Journal of College Biology Teaching, 2018
As a foundational evolutionary concept, the Hardy-Weinberg principle should be taught enthusiastically in introductory biology courses. In a companion Perspectives paper, I made the case that students are often given limited or incorrect information on the HW principle due to a lack of mastery or confidence on the part of their teachers. The…
Descriptors: Teaching Methods, Evolution, Vignettes, Introductory Courses
Shen, Jie; Zhu, Xiang; Jin, Kai; Li, Ya; Gu, YiTian; Huang, Jiahong; Qu, Yulan; Li, Xiaoyu – Biochemistry and Molecular Biology Education, 2018
The development and evaluation of a 6-hours laboratory class, based on capillary electrophoresis (CE) and the detection of microbial contaminants, is described. It can be easily scaled up or down, to suit class sizes up to 188 and completed in a shorter time scale. CE uses narrow-bore fused-silica capillaries to separate a complex array of large…
Descriptors: Science Laboratories, Science Instruction, Molecular Structure, Genetics
Hormann, Jan; Streller, Sabine; Kulak, Nora – Journal of Chemical Education, 2018
Bridging organic and inorganic chemistry as well as molecular biology, this undergraduate experiment deals with the synthesis of ligands for metal complexes that can cleave DNA. Students gain theoretical and experimental expertise about metal--DNA interactions and the mechanisms behind DNA cleavage. This experiment lays a basis for the…
Descriptors: College Science, Undergraduate Study, Chemistry, Science Instruction
Heili, Joseph M.; Gomez-Garcia, Jose; Gaut, Nathaniel J.; Cash, Brock W.; Aufdembrink, Lauren M.; Heffron, Brent A.; Shirley, Joshua D.; Carlson, Erin E.; Adamala, Katarzyna P.; Englehart, Aaron E. – Journal of Chemical Education, 2018
A teaching laboratory experiment is described where students prepare in vitro transcription reactions of a fluorescent RNA aptamer, named Broccoli, and observe the production of the aptamer in real-time on a fluorescence plate reader. Alternate visualization methods with minimal costs are also described for laboratories lacking this…
Descriptors: Science Instruction, Laboratory Experiments, Genetics, Undergraduate Students
Waldo, Jennifer Turner; Pereira, Melanie; Rahman, Mohammad; Siconolfi, Jessica – Biochemistry and Molecular Biology Education, 2018
A novel experiment has been developed with a goal of enhancing engagement and deepening understanding of fundamental molecular biology concepts. In this laboratory activity, students investigate the composition of pet foods through quantitative polymerase chain reaction (qPCR) analysis. By conducting this experiment, students address a scientific…
Descriptors: Undergraduate Students, Science Laboratories, Genetics, Animals
Ibourk, Amal; Williams, Michelle; Opperman, Amanda; Cisterna, Dante; Nazar, Christina Restrepo; Xie, Yiyu – Science Education, 2018
Genetics has become increasingly important in everyday life, a fact that is reflected in state and national science education standards. This study examines the relationship between 474 fifth graders' understandings of the core ideas of "inheritance of traits" and "variation of traits". A confirmatory factor analysis,…
Descriptors: Genetics, Science Education, Grade 5, Elementary School Students