Objective: We examined the association between microaggressions, discrimination, and transgender students' experience of food insecurity (FI). Participants: Data were from the National College Health Assessment conducted 2019-2022. Of 334,957 participants, 8,618 were transgender. Methods: Descriptive statistics and mediation analyses were calculated to test microaggressions, discrimination, and related distress, as mediators between transgender identity and FI. This study only included participants who indicated their gender identity by answering the yes/no survey question "Do you identify as transgender?" Results: Discrimination and related distress partially mediated the association between transgender identity and FI, accounting for 44% and 25%, respectively, of the total effect. Microaggressions and related distress also partially mediated this association, accounting for 49% and 30%, respectively, of the total effect. Conclusion: Experiencing discrimination and microaggressions partially explains FI among transgender students. Collaborating with stakeholder transgender students to promote food assistance programs to this population could mitigate these experiences.