Background: Accumulating evidence substantiates the adverse impact of psychological maltreatment on children's emotion regulation. Nevertheless, scant research has explored the relationship between psychological maltreatment and automatic emotion regulation (AER), along with its underlying neural mechanisms. Objective: This study aims to…

This study applied the functional near-infrared spectroscopy (fNIRS) to investigate frontal activity in autism when performing verbal fluency test and emotion recall task. We recruited 32 autistic adults without intellectual disability and 30 typically-developing controls (TDC). Prefrontal hemodynamic changes were evaluated by fNIRS when the…

While prior research has explored the neurobiological mechanisms underlying adolescent school performance, these mechanisms remain poorly understood in college students. Impulsivity has been highlighted as a key factor affecting academic success; however, its influence on the relationship between school performance and brain structure remains…

Severe psychosocial deprivation in early childhood experienced by institutionally reared children changes the course of structural brain development. Evidence from the Bucharest Early Intervention Project (BEIP) has demonstrated a causal association of random assignment to high-quality foster care intervention in early childhood with remediation…

Studies of hemispheric specialization have traditionally cast the left hemisphere as specialized for language and the right hemisphere for spatial function. Much of the supporting evidence for this separation of function comes from studies of healthy adults and those who have sustained lesions to the right or left hemisphere. However, we know…

Purpose: Rhyme increases the phonological similarity of phrases individuals hear and enhances recall from working memory. This study explores whether rhyme aids word learning and examines the underlying neural mechanisms through which rhyme facilitates word learning. Method: Fifty-seven adults completed a word learning task where they were exposed…

Procedural learning and automatization have widely been studied in behavioral psychology and typically involves a rapid improvement, followed by a plateau in performance throughout repeated training. More recently, brain imaging studies have implicated frontal-striatal brain circuits in skill learning. However, it is largely unknown whether…

Autism is associated with genomic instability, which is regulated by telomere length (TL) and index of global methylation (LINE-1). This study will determine relative TL (RTL) and LINE-1 methylation percentage for 69 patients and 33 control subjects to evaluate their potential role as biomarkers for autism. The results displayed a significant…

Concrete symbols (e.g., "sun," "run") can be learned in the context of objects and actions, thereby grounding their meaning in the world. However, it is controversial whether a comparable avenue to semantic learning exists for abstract symbols (e.g., "democracy"). When we simulated the putative brain mechanisms of…

Recent studies show that oxidative stress has an important role in the etiology of autism. In our study, Nrf2, which is the main regulator of cellular antioxidant response, and Keap1 and Gsk-3[beta], which are the main proteins that regulate this pathway, were compared between children with autism and healthy controls. To the best of our…

The fast pace and relative ease at which individuals with typical language acquire and use words belie the complexity and vulnerability of lexical representation development (i.e., word learning) and lexical-semantic processing. Lexical-semantic processing impairments are common in both developmental and acquired communication disorders and, even…

Metacognitive calibration--the capacity to accurately self-assess one's performance--forms the basis for error detection and self-monitoring and is a potential catalyst for conceptual change. Limited brain imaging research on authentic learning tasks implicates the lateral prefrontal and anterior cingulate brain regions in expert scientific…

Human intelligence has the ability to capture abstract concepts from experience and utilize that learned knowledge for adaptation to new situations. Lifelong machine learning aims to achieve those same properties of human intelligence by designing algorithms to learn from a sequence of tasks, extract useful knowledge of previous tasks, and re-use…

A significant number of individuals with tuberous sclerosis complex (TSC) exhibit language difficulties. Here, we examined the language-related brain morphometry in 59 participants (7 participants with TSC and comorbid autism spectrum disorder (ASD) (TSC + ASD), 13 with TSC but no ASD (TSC-ASD), 10 with ASD-only (ASD), and 29 typically developing…

Research in verbal and visual narratives has often emphasized backward-looking inferences, where absent information is subsequently inferred. However, comics use conventions like star-shaped "action stars" where a reader "knows" events are undepicted "at that moment," rather than omitted entirely. We contrasted the…