The aim of this study is to investigate excitability changes in the human motor cortex induced by variable therapeutic electrical stimulations (TESs) with or without voluntary drive. We recorded motor-evoked potentials (MEPs) from extensor and flexor carpi radialis (FCR) muscles at rest and during FCR muscle contraction after the application of…

Aim: Dystonia in childhood has many causes. Imaging may suggest corticospinal tract dysfunction with or without coexistent basal ganglia damage. There are very few published neurophysiological studies on children with dystonia; one previous study has focused on primary dystonia. We investigated central motor conduction in 62 children (34 males, 28…

Composition is learned by discovering that musical ideas can be experienced in a variety of ways, and that new musical ideas can be created by reconfiguring learned materials in new contexts. The act of imagining, defining, and communicating unique musical ideas awakens in young people a dormant part of their brains, unlocking an awareness of the…

We present two phenotypically similar females with Xp duplication who have autism and epilepsy. Case 1 is a 14-year-old Honduran female with autism and medically refractory complex partial, secondarily generalized epilepsy. Case 2 is a 3-year-old Austrian female with autism and medically refractory complex partial epilepsy. Both patients also…

This article examines the extent to which lexical bundles (LBs; i.e., frequently recurring strings of words that often span traditional syntactic boundaries) are stored and processed holistically. Three self-paced reading experiments compared sentences containing LBs (e.g., "in the middle of the") and matched control sentence fragments (e.g., "in…

Mechanisms of cortical reorganization underlying the enhancement of speech processing have been poorly investigated. In the present study, we addressed changes in functional and effective connectivity induced in subjects who learned to deliberately increase activation in the right inferior frontal gyrus (rIFG), and improved their ability to…

The human temporal lobe is well known to be critical for language comprehension. Previous physiological research has focused mainly on non-invasive neuroimaging and electrophysiological techniques with each approach requiring averaging across many trials and subjects. The results of these studies have implicated extended anatomical regions in…

Semantic processing in 10-year-old children and adults was examined using event related potentials (ERPs). The N400 component, an index of semantic processing, was studied in relation to sentences that ended with congruent, moderately incongruent, or strongly incongruent words. N400 amplitude in adults corresponded to levels of semantic…

The identity and distribution of neurons that are involved in any learning or memory event is not known. In previous studies, we identified a discrete population of neurons in the lateral amygdala that show learning-specific activation of a c-"fos"-regulated transgene following context fear conditioning. Here, we have extended these studies to…

Participants made categorical or coordinate spatial judgments on the global or local elements of shapes. Stimuli were composed of a horizontal line and two dots. In the Categorical task, participants judged whether the line was above or below the dots. In the Coordinate task, they judged whether the line would fit between the dots. Stimuli were…

An examination of the 2005-2010 online archives of major American network news stations and newspapers reveals a troubling picture for music education. News stories frequently mention the disappearance of music education. When the media mention the existence of music education, they often promote it as a means of raising standardized test scores…

Electrophysiological studies investigating similarities between music and language perception have relied exclusively on the signal averaging technique, which does not adequately represent oscillatory aspects of electrical brain activity that are relevant for higher cognition. The current study investigated the patterns of brain oscillations…

A role for rostral prefrontal cortex (BA10) has been proposed in multitasking, in particular, the selection and maintenance of higher order internal goals while other sub-goals are being performed. BA10 has also been implicated in the ability to infer someone else's feelings and thoughts, often referred to as theory of mind. While most of the data…

Brain growth and change are key factors in adolescent development and influence cognitions, emotions, and behavior. Much of the research on the adolescent brain is fairly recent, and mental health practitioners working with adolescents must have knowledge about these changes to more effectively engage their young clients in therapy. The…

A same-different task was used to test the hypothesis that musical expertise improves the discrimination of tonal and segmental (consonant, vowel) variations in a tone language, Mandarin Chinese. Two four-word sequences (prime and target) were presented to French musicians and nonmusicians unfamiliar with Mandarin, and event-related brain…