An important cellular mechanism contributing to the strength and duration of memories is activity-dependent alterations in the strength of synaptic connections within the neural circuit encoding the memory. Reversal of the memory is typically correlated with a reversal of the cellular changes to levels expressed prior to the stimulation. Thus, for…

It has been more than 50 years since the first description of ocular dominance plasticity--the profound modification of primary visual cortex (V1) following temporary monocular deprivation. This discovery immediately attracted the intense interest of neurobiologists focused on the general question of how experience and deprivation modify the brain…

Although significant advances have been made in our understanding of the neural basis of learning and memory over the past hundred years, the translation of these neuroscientific insights into classroom teaching practice has been very limited. In this review, we discuss the historical development of pedagogy, cognitive psychology, and the…

The medial prefrontal cortex (mPFC) and the right temporo-parietal junction (rTPj) are highly involved in social understanding, a core area of impairment in autism spectrum disorder (ASD). We used fMRI to investigate sex differences in the neural correlates of social understanding in 27 high-functioning adults with ASD and 23 matched controls.…

Autism spectrum disorder (ASD) is characterized by atypical visual perception both in the social and nonsocial domain. In order to measure a reliable visual response, visual evoked potentials were recorded during a passive pattern-reversal stimulation in adolescents and adults with and without ASD. While the present results show the same…

Mathematical disabilities (MD) have a negative life-long impact on professional success, employment, and health outcomes. Yet little is known about the intrinsic functional brain organization that contributes to poor math skills in affected children. It is now increasingly recognized that math cognition requires coordinated interaction within a…

There is growing interest in generalization of learned contextual fear, driven in part by the hypothesis that mood and anxiety disorders stem from impaired hippocampal mechanisms of fear generalization and discrimination. However, there has been relatively little investigation of the behavioral and procedural mechanisms that might control…

Brain Gym is a movement-based program designed to address a diverse range of students academic and behavioral needs by promoting whole-brain learning. However, the scientific research-base supporting Brain Gym is limited and findings are inconclusive. This study's goal was to evaluate the effects of Brain Gym movements on fourth grade students…

In this dissertation, we present three empirical studies exploring the relationship between the central planning processes of spoken word production--lexical selection, phonological encoding, and phonetic encoding--and three other cognitive processes traditionally considered separate or peripheral to this core system. Study 1 examines the role of…

Many kindergarten teachers have encountered children who enter school lacking the ability to control their behavior, but they may not understand the social and biological processes behind these children's disruptive behavior. The author reviews research into early childhood brain development to explain how trauma and chronic stress can make it…

Background: The ability to generate words that follow certain constraints, or verbal fluency, is a sensitive indicator of neurocognitive impairment, and is impacted by a variety of variables. Aims: To investigate the effect of post-stroke aphasia, elicitation category and linguistic variables on verbal fluency performance. Methods &…

This study investigated whether brain-derived neurotrophic factor (BDNF) genotype moderated inhibitory control during an emotionally valenced task in a sample of internationally adopted adolescents (N = 109, ages 12-13 years) who spent their early years in institutional care. Participants were genotyped for the Val66Met polymorphism of the BDNF…

This study aims at investigating the impact of brain-based learning on the retention of English language knowledge amongst young adult learners. The participants were subjected to an intervention in brain-based learning principles for approximately four and a half months. The results of the proficiency exams administered at the beginning of and…

More has been learned about the human brain in the past few decades than in the whole prior history of humanity. In this article Richard Barbieri considers learning and the brain from a few different perspectives. He begins by examining the practice of neuroscience itself and what was understood about the brain before neuroscience. This leads to a…

Despite the fact that the cannabinoid receptor type 1 (CB1R) plays a pivotal role in emotional memory processing in different regions of the brain, its function in the retrosplenial cortex (RSC) remains unknown. Here, using contextual fear conditioning in rats, we showed that a post-training intra-RSC infusion of the CB1R antagonist AM251…