Background: Despite work on the self-identities of people with intellectual disabilities, research has yet to describe the self-perceptions of people with Prader-Willi syndrome (PWS). The perspectives of those with PWS are also important for rapidly evolving clinical trials aimed at treating symptoms of PWS. Method: Twenty-one young people with…

Background: Educational attainment is connected to many important life outcomes, and the previous research has already focused on identifying its genetic and environmental components. However, most of these studies used twin data only and did not incorporate information from other family members. Twin studies typically decompose the phenotypic…

Autism spectrum disorder is a neurodevelopmental disorder in which genetic factors play key roles. Limited research has been conducted on genetic testing of children with autism spectrum disorder in low middle-income countries. This prospective cross-sectional study was conducted at the pediatric neurology clinics of three university hospitals in…

Objective: This study aimed to assess the quality and readability of web-based information on familial hypercholesterolaemia. Design, setting and methods: Internet searches using the terms 'familial hypercholesterolemia', 'hypercholesterolemia', 'inherited high cholesterol', 'hereditary high cholesterol' and 'inherited high LDL' were conducted…

Although biochemistry is fascinating to undergraduates regardless of their major, the complexity involved requires a great deal of effort and leads many to perceive it to be an intense, facts-based course limiting personal creativity. This activity takes the fundamental knowledge associated with inducible promoters and combines it with the…

DNA analysis is a common diagnostic tool in healthcare: ranging from microbial typing (e.g. DNA strands of viral, bacterial and even fungal pathogens), oncological screen (e.g. Breast cancer detection via DNA analysis of any BRCA gene mutations), genetic amniocentesis test (a medical technique used in determining chromosomal conditions such as…

This study describes the profile of repetitive behaviour in individuals with Williams syndrome, utilising cross-syndrome comparisons with people with Prader-Willi and Down syndromes. The Repetitive Behaviour Questionnaire was administered to caregivers of adults with Williams (n = 96), Prader-Willi (n = 103) and Down (n = 78) syndromes. There were…

CRISPR (also known as CRISPR-Cas9) is a powerful biotechnology tool that gives scientists unprecedented access to the genetic makeup of all living organisms, including humans. It originally evolved as an adaptive immune system in bacteria to defend against viruses. When artificially harnessed in the laboratory it allows scientists to accurately…

Howard Gardner's longtime interest in the range of human capacities and talents was facilitated by his leadership role in the Bernard Van Leer Foundation "Project on Human Potential" carried out at the Harvard Graduate School of Education in 1979-1985. In this reflective essay, Gardner describes his early studies of human potential and…

In this article, we describe an in-house polymerase chain reaction-sequence specific priming (PCR-SSP) assay designed for undergraduate medical students as part of the experimental pathogen biology and immunology (EPBI) course. It screens human leukocyte antigen (HLA)-DR2 allotype from genomic DNA samples using a rapid and single-tube PCR…

With the global increase of infections caused by antibiotic-resistant bacterial strains, there is an urgent need for new methods of tackling the issue. Genomic analysis of bacterial strains can help to understand their virulence and antibiotic resistance profile. Bioinformatic skills are in great demand across the biological sciences. We designed…

This review aimed to investigate the use of the Cambridge Neuropsychological Automated Testing Battery (CANTAB) for people at risk of cognitive impairment, especially those born with Down syndrome and those born preterm. Six databases were searched according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) standards,…

Competency in mathematics is needed to respond to the vast employment opportunities available in the STEM sectors. These employment opportunities all require basic foundational mathematics skills, yet there is a shortfall of mathematics abilities due, in-part, to mathematics anxiety. Mathematics anxiety can surface as fear and avoidance of…

In the present research, the "DNA Model with Clothespins" activity was designed to teach the subjects of nucleotide, DNA, and DNA replication, which are abstract subjects of science. The aim of the research, which was carried out with 20 students in 8th grade, was to examine the effects of the activity on students' achievement on the…

We examined widely used popular calculus textbooks to explore opportunities to learn the limit concept. Definitions, worked problems, and exercise problems were coded to examine if these tasks allow students to use informal thinking to coordinate domain and range processes to understand the infinite process of limit. Results revealed many exercise…