Drug repurposing refers to the process of discovering new therapeutic uses for existing medicines. Compared to traditional drug discovery, drug repurposing is attractive for its speed, cost, and reduced risk of failure. However, existing approaches for drug repurposing involve complex, computationally-intensive analytical methods that are not…

In parallel process latent growth curve mediation models, the mediation pathways from treatment to the intercept or slope of outcome through the intercept or slope of mediator are often of interest. In this study, we developed causal mediation analysis methods for these mediation pathways. Particularly, we provided causal definitions and…

Mediation analysis is widely applied in various fields of science, such as psychology, epidemiology, and sociology. In practice, many psychological and behavioral phenomena are dynamic, and the corresponding mediation effects are expected to change over time. However, most existing mediation methods assume a static mediation effect over time,…

Mediation analysis is widely applied in various fields of science, such as psychology, epidemiology, and sociology. In practice, many psychological and behavioral phenomena are dynamic, and the corresponding mediation effects are expected to change over time. However, most existing mediation methods assume a static mediation effect over time,…

This study examined the false positive (FP) rates and sensitivity of Bayesian fit indices to structural misspecification in Bayesian structural equation modeling. The impact of measurement quality, sample size, model size, the magnitude of misspecified path effect, and the choice or prior on the performance of the fit indices was also…

Students' reading ability affects their outcomes in learning software even outside of reading education, such as in math education, which can result in unexpected and inequitable outcomes. We analyze an adaptive learning software using Bayesian Knowledge Tracing (BKT) to understand how the fairness of the software is impacted when reading ability…

A hallmark of effective teaching is that it grants learners not just a collection of facts about the world, but also a toolkit of abstractions that can be applied to solve new problems. How do humans teach abstractions from examples? Here, we applied Bayesian models of pedagogy to a necklace-building task where teachers create necklaces to teach a…

Previous psychophysical studies reported a positive aftereffect in tactile temporal order judgments, which can be explained by the Bayesian estimation model ('Bayesian calibration'). We investigated the relationship between Bayesian calibration and autistic traits in participants with typical development (TD) and autism spectrum disorder (ASD).…

Though individual categorization or decision processes have been studied separately in many previous investigations, few studies have investigated how they interact by using a two-stage task of first categorizing and then deciding. To address this issue, we investigated a categorization-decision task in two experiments. In both, participants were…

To evaluate multidimensional factor structure, a popular method that combines features of confirmatory and exploratory factor analysis is Bayesian structural equation modeling with small-variance normal priors (BSEM-N). This simulation study evaluated BSEM-N as a variable selection and parameter estimation tool in factor analysis with sparse…

An operational multistage adaptive test (MST) requires the development of a large item bank and the effort to continuously replenish the item bank due to concerns about test security and validity over the long term. New items should be pretested and linked to the item bank before being used operationally. The linking item volume fluctuations in…

We first review existing literature on cumulative logit models along with various ways to test the parallel lines assumption. Building on the traditional frequentist framework, we introduce a method of Bayesian assessment of null values to provide an alternative way to examine the parallel lines assumption using highest density intervals and…

This article is concerned with the large-sample parameter estimator behavior in applications of Bayesian confirmatory factor analysis in behavioral measurement. The property of strong convergence of the popular Bayesian posterior median estimator is discussed, which states numerical convergence with probability 1 of the resulting estimates to the…

Background: The potential of learning analytics dashboards in virtual reality simulation-based training environments to influence occupational self-efficacy via self-reflection phase processes in the Chemical industry is still not fully understood. Learning analytics dashboards provide feedback on learner performance and offer points of comparison…

This research aims to compare the ability and item parameter estimations of Item Response Theory according to Maximum likelihood and Bayesian approaches in different Monte Carlo simulation conditions. For this purpose, depending on the changes in the priori distribution type, sample size, test length, and logistics model, the ability and item…