The stereoselective synthesis of an aryl vinyl bromide is accomplished in a rapid microscale reaction of "trans"-4-methoxycinnamic acid with N-bromosuccinimide in dichloromethane. The product is purified by dry column vacuum chromatography and its stereochemistry is determined by [superscript 1]H NMR. TLC, GC and GC-MSD can also be used. This…

Circular dichroism spectroscopy was used to measure the thermal unfolding of bovine pancreatic ribonuclease A (RNase A) with various concentrations of guanidine hydrochloride (GuHCl). A red shift in transition midpoint temperatures, T[subscript m], occurred with increasing concentration of the strong protein denaturant. van Hoff enthalpy changes,…

This article describes an experiment, designed by Cindy Henk, manager of the Socolofsky Microscopy Center at Louisiana State University (LSU), that involved collecting and viewing microorganisms in the air-water interface. The experiment was participated by Leesville High School microbiology students. The students found that the air-water…

Although English lacks 1-to-1 relationships between sounds and spellings, considering the context in which a phoneme occurs can often aid in selecting a spelling. For example, /a/ is typically spelled as a when it follows /w/, as in wand, but as o when it follows other consonants, as in pond. In 2 experiments, the authors asked whether children's…

In the US debate over science-based educational research, experimentation is again coming to the fore as ideal for establishing an evidence base of what works in educational interventions thus contributing to the climate of accountability in educational research and practice. Mixed methods research is being positioned in this discussion as a…

A number of thought experiments are cited, some well-known, some not. These illustrate the power of thought experiments. Other examples are given that show some of the dangers. As well as examples from the science, some examples of visual reasoning from mathematics are also presented, again with an eye to illustrating their promise and perils.…

The transformation of 346 chemistry courses into a training experience that could provide undergraduate students with a skill set essential for a research-based chemistry career is presented. The course has an innovative structure that connects undergraduate students with graduate research labs at the semester midpoint and also includes new,…

In April 2005 the World Year of Physics (Einstein Year in the UK and Ireland) was celebrated with an Einstein week in Stockholm House of Science. Seven experiments illustrated Einstein's remarkable work in 1905 on Brownian motion, the photoelectric effect and special relativity. Thirteen school classes with 260 pupils, 30 teachers and 25 members…

Demonstrations are sometimes perceived as merely entertaining and expendable ancillaries for lectures and laboratory sessions. Nothing can be further from the truth. If done properly, demonstrations have much more value than lectures and labs when used to teach critical thinking in the sciences. There are effective ways to model scientific…

A serendipitous finding involving static magnetic fields can be used to design experiments suitable for both science and nonscience majors. It has been reported that organisms respond differently to high-gauss magnetic fields generated by north poles than they do to those generated by south poles. Experimental tests of this hypothesis are ideal…

This article presents how Stevens Institute of Technology (SIT) has adopted an Internet-based approach to implement its undergraduate student laboratories. The approach allowed student interaction with the experimental devices from remote locations at any time. Furthermore, it enabled instructors to include demonstrations of sophisticated…

Several chemical concepts to the extraction of a water pollutant OPC (octylphenoxyacetic acid) is presented. As an introduction to the laboratory experiment, a discussion on endocrine disrupters is conducted to familiarize the student with the background of the experiment and to explain the need for the extraction and quantitation of the OPC which…

A laboratory project permits for the discussion of the reaction mechanism of the Suzuki-Miyaura coupling reaction. The practical part of the project makes the students familiar with working under inert atmosphere but if the appropriate equipment for working under inert atmosphere is not available in a laboratory, novel catalysts that do not…

This experiment examined the effects of reinforcement probability on resistance to change of remembering and response rate. Pigeons responded on a two- component multiple schedule in which completion of a variable-interval 20-s schedule produced delayed matching-to-sample trials in both components. Each session included four delays (0.1 s, 2 s, 4…

This communication discusses preliminary results on an experimentation of e-Learning with MIS students, mainly in order to cope with the logistics of lab organization. A learning management software was installed which changed completely the learning process, from content to logistics. Students have expressed their satisfaction with the e-Learning…