Delay eyeblink conditioning is established by paired presentations of a conditioned stimulus (CS) such as a tone or light, and an unconditioned stimulus (US) that elicits the blink reflex. Conditioned stimulus information is projected from the basilar pontine nuclei to the cerebellar interpositus nucleus and cortex. The cerebellar cortex,…

The discussion of the Blau (1936) article continues the welcome tradition established in this journal in acquainting readers with historically important articles in the history of ADHD. That history began with efforts to understand the functions of the brain likely to be impaired from injury to various brain regions and especially the frontal…

Objective: Previous studies have shown smaller brain volume and less gray matter in children with attention-deficit/hyperactivity disorder (ADHD). Relatively few morphological studies have examined structures thought to subserve inhibitory control, one of the diagnostic features of ADHD. We examined one such region, the pars opercularis,…

When subjects are given the balls-and-boxes problem-solving task (Kotovsky & Simon, 1990), they move rapidly towards the goal after an extended exploratory phase, despite having no awareness of how to solve the task. We investigated possible non-conscious learning mechanisms by giving subjects three runs of the task while recording ERPs. Subjects…

The current study compared the neural correlates of associative retrieval of compound (unitized) stimuli and unrelated (non-unitized) stimuli. Although associative recognition was nearly identical for compounds and unrelated pairs, accurate recognition of these different pair types was associated with activation in distinct regions within the…

Human observers use prior constraints to disambiguate a scene; in particular, light is preferentially seen as coming from above but also slightly from the left. One explanation of this lateral bias could be a cerebral hemispheric difference. The aim of the present study was to determine the preferred light source position for neglect patients. For…

An effective connectivity study was carried out on 16 young, healthy subjects performing an alertness task. The objective of this study was to develop and to evaluate a putative network model of alertness by adapting structural equation modeling to fMRI data. This study was designed to evaluate the directed interactivity of an attentional network…

Physical and Name Identity letter-matching tasks were used to explore differences in interhemispheric collaboration in younger and older adults. To determine whether other factors might also be related to across/within-hemisphere processing or visual field asymmetries, neuropsychological tests measuring frontal/executive functioning were…

Working memory is devoted to the temporary storage and on-line manipulation of information. Recently, an integrative system termed the episodic buffer has been proposed to integrate and hold information being entered or retrieved from episodic memory. Although the brain system supporting such an integrative buffer is still in debate, the medial…

We hypothesized that facial attractiveness represents a dual judgment, a combination of reward-based, sexual processes, and aesthetic, cognitive processes. Herein we describe a study that demonstrates that sexual and nonsexual processes both contribute to attractiveness judgments and that these processes can be dissociated. Female participants…

Using a two-way signaled active avoidance (2-AA) learning procedure, where rats were trained in a shuttle box to avoid a footshock signaled by an auditory stimulus, we tested the contributions of the lateral (LA), basal (B), and central (CE) nuclei of the amygdala to the expression of instrumental active avoidance conditioned responses (CRs).…

To test the effects of providing relational cues at encoding and/or retrieval on multi-trial, multi-list free recall in adults with high-functioning autism spectrum disorder (ASD), 16 adults with ASD and 16 matched typical adults learned a first followed by a second categorised list of 24 words. Category labels were provided at encoding,…

In the language domain, most studies of error monitoring have been devoted to language production. However, in language perception, errors are made as well and we are able to detect them. According to the monitoring theory of language perception, a strong conflict between what is expected and what is observed triggers reanalysis to check for…

The current study examined the relationship between a prognostic indicator of vascular health, flow-mediated dilation (FMD), and working memory-related brain activation in healthy middle-aged adults. Forty-two participants underwent functional magnetic resonance imaging while completing a 2-Back working memory task. Brachial artery…

To investigate attentional shifting in perihand space, we measured performance on a covert visual orienting task under different hand positions. Participants discriminated visual shapes presented on a screen and responded using footpedals placed under their right foot. With the right hand positioned by the right side of the screen, mean cueing…