An experiment for the synthesis of N-acyl derivatives of natural amino acids has been developed as part of the Distributed Drug Discovery (D3) program. Students use solid-phase synthesis techniques to complete a three-step, combinatorial synthesis of six products, which are analyzed using LC-MS and NMR spectroscopy. This protocol is suitable for…

The stated purpose of this paper is to provide a simple and quick method to assemble pH electrodes using readily available materials. The present assembled electrodes are comparable with commercial pH electrodes, with accuracy for pH determination in the range 2-12. Furthermore, the constructed simple pH electrodes exhibit a fast and stable…

The CRISPR/Cas9 system is a powerful tool for gene editing and it has become increasingly important for biology students to understand this emerging technique. Most CRISPR laboratory teaching modules use complex metazoan systems or mammalian cell culture which can be expensive. Here, we present a lab module that engages students in learning the…

The synthesis of substituted 1,4-benzoquinones, a biologically important class of compounds, was developed using [mu]-oxodi(phenyliodanyl) diacetate, a (diacetoxyiodo)benzene-based oxidizing reagent, in order to introduce second-year undergraduate organic laboratory students in their second semester or advanced organic students to increasingly…

Quantum dots (QDs) are considered useful for demonstrating quantum phenomena in undergraduate laboratories due to their monodisperse size and excellent optical properties. Although doping has an increasingly important role in QD fabrication in the semiconductor field, it has rarely been discussed in the context of the undergraduate laboratory. In…

The concepts of phospholipase activity is often taught in undergraduate biology and biochemistry classes and reinforced in laboratory exercises. However, very rarely does the design of these exercises allow students to directly gain experience in the use of modern instruments such as digital imaging systems and fluorescence spectrophotometers. The…

The effect of surfactant adsorption on surface tension, as well as associated thermodynamic concepts are introduced in a laboratory experiment designed for undergraduate students. Using a reliable and accessible method, students measure the surface tension of aqueous solutions at different concentrations of sodium dodecyl sulfate. Students collect…

We have developed a laboratory project in which students prepare liposomes, expose them to hyperosmotic and hypoosmotic solutions, and follow the resulting shrinking and swelling (respectively) with laser light scattering. Each light intensity transient can be fit to an exponential decline or rise, with the decay constant (k) and the amplitude…

In this paper we present a study on the capillary action of water in a glass tube. It is a well-known phenomenon that the rise of a water column in the capillary is governed by parameters such as surface tension of water, radius of the tube, density of water and acceleration due to gravity. The interdependence of the parameters gives rise to the…

Old physics textbooks give us a great opportunity to learn about the history of science and rediscover different methods to teach physics to our students. There are many disused and forgotten experiments in them, but these can still be very useful to affirm and understand physics. This is the case of an instrument used in the 19th century to…

As a universal and extensively adopted technique, enzyme-linked immunosorbent assay (ELISA) can be used to detect and quantify small molecules in many applications both clinical and analytical. However, generally, students experiment mechanically using commercial ELISA kits according to the instructions and eventually produce a standard curve to…

Each student's individual experience in learning is very important. Lower secondary school students are engaged in activities that focus on inquiry rather than the acquisition of scientific knowledge in science classrooms. Therefore, the experiences and thoughts of lower secondary school students in the stage of scientific inquiry need to be…

Student ethnicity is one of the internal factors that influence student learning. Bacteriology is a course that examines prokaryotic unicellular living things and is practiced in laboratories that need to implement projects. The aim of this research is to know the distribution of students based on their ethnicity. The research sample was students…

Online laboratories can be an effective way to introduce students to lab concepts while providing flexibility, increased access, and reduced costs. However, online labs might lack the authentic research experience that can be gained by doing hands-on lab work. This study explores student perceptions of an online, inquiry-based introductory biology…

Virtual experiments offer opportunities for students to engage in the scientific process and observe scientific phenomena. However, virtual experiments are not always effective for learning. The current study examined how two small manipulations might support better learning from virtual experiments and the extent to which this varied across…