Development of key practical skills is fundamental to bioscience courses in higher education. With limitations on access to laboratory time due to the COVID-19 pandemic, a "Bioskills at home" kit was developed to create opportunities for first year undergraduate students to develop these skills using online support resources to guide…

According to variation theory, it is essential to enable students to focus on the object of learning and discern its critical features, but the features that "it is possible" to discern often depend on the equipment used. Thus, in labs, the experimental technologies used may shape students' experience of focal phenomena, in a…

Exposure of organisms to high temperatures and various chemical and physical stressors can cause protein misfolding and aggregation. In turn, this can disrupt the functions of proteins, threatening both development and homeostasis. To overcome this, cells can initiate the highly conserved heat shock (HS) stress response pathway. In eukaryotes,…

Assessment is a central component of course curriculums and is used to certify student learning, but it can also be used as a tool to improve teaching and learning. Many laboratory courses are structured such that there is only a grade for a particular laboratory, which limits the insights that can be gained in student learning. We developed a…

Semimicro pressure filtration is carried out by pressurizing a suspension through pushing the piston of a gas-filled plastic syringe whose needle perforates the closure of a cylindrical filter funnel. Basic features as well as pros and cons of vacuum and pressure filtration are pointed out and compared to support rational choice between the two…

It is a well known fact that the Earth carries a net negative charge that produces a downward electrostatic field. The present experiment shows how this field can be measured with a Field Mill which has been constructed from components readily available in the Laboratory. In fine weather conditions a value of 120 (±10) V m[superscript -1] was…

Most biochemical transformations involve more than one substrate. Bisubstrate enzymes catalyze multiple chemical reactions in living systems and include members of the transferase, oxidoreductase, and ligase enzyme classes. Working knowledge of bisubstrate enzyme kinetic models is thus of clear importance to the practicing biochemist. However,…

Much of analytical chemistry involves the analysis of complex mixtures, where careful attention to sample preparation and method selectivity is required to avoid interferents and obtain accurate data. As this type of analysis is very different from simple colorimetric analysis that most students are exposed to in general chemistry, this laboratory…

Developing simpler, more accessible, and more affordable methods for the determination of the boiling point of microscale amounts of liquid may lead to increased utilization in research and teaching laboratories as an analytical technique. Our efforts toward that goal have revealed that digital hot plates can be used as the heat source. One option…

The CRISPR/Cas9 system opens new horizons (M. Adli, Nat Commun, 2018) regarding genetic modifications of living organisms but also as an in vitro tool in laboratory protocols. Therefore, it boosts possibilities in research and future medical treatments. As the controversial claim of genomically edited babies by He Jiankui (Cyranoski D., Nature,…

This is an easy and inexpensive laboratory experiment in which undergraduate students at the Bachelor's degree level in Chemistry can measure formation constants of complexes [Ni(en)[subscript n](OH[subscript 2])[subscript 6-2n]][superscript 2]+ (n = 1, 2 or 3; en = ethylenediamine) through an acid-base titration. The background information…

This essay assessed the chemical safety knowledge of students in the School of Chemistry and Chemical Engineering, Tianjin University of Technology, concerning chemical storage, heat operation, waste disposal, and emergency response. The results show that students' familiarity and understanding of safety knowledge is not satisfactory, especially…

A multistep synthesis of a novel arylidene 3­(2"H")-furanone has been designed and optimized for the second-year organic laboratory. The three-step sequence consists of a nucleophilic substitution, intramolecular cyclization, and acid-catalyzed aldol condensation, and can be carried out within two 3 h laboratory periods. The final…

To this day, autopsies and dissections have been essential in medical education, but declining autopsy numbers have endangered this long-standing tradition. Students' perceptions of these teaching methods should be constantly updated to help educators understand how to achieve their teaching goals. The purpose of this study was to explore the…

Although the methods for medical education continue to evolve due to the development of medicines, the cadaver dissection course still plays a fundamental role. The cadaver dissection course allows students to learn to handle instruments correctly while actively exploring three-dimensional anatomy. However, dissection comes with the risk of…