Background: Autism spectrum disorder (ASD) is associated with high rates of psychiatric disturbance to include attention-deficit/hyperactivity disorder (ADHD), tic disorder, and anxiety disorders. The aim of the present study was to examine the association between a variable number tandem repeat (VNTR) functional polymorphism located in the…

The "co-familiality" criterion for an endophenotype has two requirements: (1) clinically unaffected relatives as a group should show both a shift in mean performance and an increase in variance compared with controls; (2) performance scores should be heritable. Performance on the antisaccade task is one of several candidate endophenotypes for…

CHARGE syndrome is characterized by multiple physical abnormalities, and impaired vision and hearing. In this pilot study, communication in the early stage of language development in three one- to eight-year-old children with CHARGE syndrome was explored using video recorded free-play interaction sessions and a parental questionnaire. The children…

Discusses insights discovered from research into human biology that are raising possibilities for therapy, prevention of disease, and challenges to society in the form of ethical decisions about the appropriate application of genetic information. (Author/RT)

Rulings on applications for animal patents being considered by the U.S. Patent and Trademark Office could profoundly influence university patent and research income. Many animal-rights advocates have expressed philosophical objections to genetic engineering of animals. (MLW)

Discusses some of the major genetic information processes which may be modeled by computer program string manipulation, focusing on replication and transcription. Also discusses instructional applications of using string models. (JN)

The genetic study of ADHD has made considerable progress. Further developments in the field will be reliant in part on identifying the most appropriate phenotypes for genetic analysis. The use of both categorical and dimensional measures of symptoms related to ADHD has been productive. The use of multiple reporters is a valuable feature of the…

Author has spent a life-time working in the field of educational psychology and related disciplines. Here he focuses on the concept of intelligence. (Editor/RK)

Research in human genetics is now expanding rapidly, leading to increasingly precise ways of preventing or treating some of the 2,000 or more inherited disorders that afflict human beings. At the same time, it has produced a wealth of new ideas and techniques which are laying the groundwork for new medical science for the 21st century. Recent work…

It is argued that numerical peculiarities in Burt's reports of kinship correlations are more reasonably attributable to carelessness than to fraud. No analysis shows that Burt's results are biased so as to favor his theory, and they are in close agreement with numerous independent studies. (Author/AM)

The importance of cytogentic studies, including banding techniques, in moderately retarded individuals without significant physical anomalies was pointed out by the analysis of a moderately retarded 10 year old, non-Down's female. (BB)

Satisfaction with professional-client encounters was ascertained from 173 genetic counselors. Professional satisfaction was not associated with client learning of medical information or with discussion of items of greatest concern to clients. The major correlates were perceptions that they were communicating knowledge successfully. (Author/JOW)

Argues for unifying the conceptual frameworks of theories of evolution so that problems and their solutions in one theory may be transposed and explored in the others. The argument is used to reconsider the mutationist and Darwinian theories of evolution in the light of Piaget's nonstandard theory of evolution. (Author/RH)

The author responds to a review of replicated findings about stuttering and examines issues related to its possible genetic source, the role of hemispheric assymetries, and fluency-inducing conditions. A theoretical framework for the replicated findings is explored. (CL)