Critically reviews literature relevant to the hypothesis that a major X-linked gene determines spatial ability in man. It is concluded that belief in the validity of the hypothesis is unfounded. (Author/SS)

Describes development of the limb and various interactions necessary for the expression of its unique form and phenotypes to uncover the hierarchical controlling steps in the development process for the potential of avoiding abnormal events and manipulating what might be detrimental genetic events into a normal sequence. (Author/SK)

Reports a review of 13 genetics textbooks published from 1975 to 1979. Six tables present summaries of the significant data about the books, specific topics covered in the texts, and the number of pages devoted to each of 15 general topics in each textbook evaluated. (CS)

This paper attempts to describe the psychopathology of the borderline patient. Descriptive features of the syndrome in children, adults, and adolescents are given. Genetic considerations and psychic structures are discussed with their resulting treatment implications. Finally, outpatient treatment strategies are presented in detail, including…

Explores longitudinal data on sex, height and weight differences among pubescent monozygotic and dizygotic twins for theoretical implications related to heredity-environment interaction effects. (RH)

Three models of behavioral effects of genetic disorders characterized by mental retardation were compared: (1) no-specific effect model (all genetic disorders have identical behavioral outcomes); (2) totally specific model (each genetic disorder has unique outcomes); and (3) partially specific model (two or more genetic disorders share outcomes…

ApoE gene polymorphism was examined in 100 adults with Down syndrome with and without dementia (Alzheimer's disease) and 346 control subjects. Additionally, a meta analysis of studies (total N=480 subjects) was performed. Results indicated a similar incidence of the gene across groups but subjects with the allele tended to an earlier onset of…

Describes how to use various types of licorice ropes to illustrate the similarities between RNA and DNA. Specifically addresses illustrations of replication, transcription, protein synthesis, mitosis, meiosis, mutations, and anomalies. (DDR)

Selective abortion of fetuses with Down syndrome is discussed in terms of abortion perspectives, genetic testing, legislation, and ethical principles. The ethical principles of autonomy, beneficence, nonmaleficence, fidelity, and justice are offered as guidelines for the examination of legal standards imposed by legislation. (Author/PB)

Evidence for the genetic basis of autism is offered, as is evidence that environmental determinants also play a role. Research involving the Human Genome Project, using linkage analysis with affected autistic sibling pairs to identify polymorphic marker genes, is described and proposed. (DB)

Suggests that computer science analogies can aid the understanding of gene expression, including the storage of genetic information on chromosomes. Presents a matrix of biology and computer science concepts. (DDR)

Explains the use of genetic algorithms to combine results from multiple query evaluations to improve relevance in information retrieval. Discusses niching techniques, relevance feedback techniques, and evolution heuristics, and compares retrieval results obtained by both genetic multiple query evaluation and classical single query evaluation…

Examines the influence of apolipoprotein E gene states on three cognitive outcomes in 173 people at age 11 and in the same people at age 77 and examined the change in IQ between these ages. There was no significant main effect of gene status on IQ in youth or old age, nor in cognitive change across the lifespan. (SLD)

Describes a sophisticated version of the fruit fly experiment for teaching concepts about genetics to biology students. Provides students with the opportunity to work with live animals over an extended period. (JRH)

For pairs of full siblings, half-siblings, and cousins, analyzed maternal ratings of children's behavior problems at three times between ages 4 and 10. Found that nonshared environmental influences were substantial at each age but did not contribute to continuities in children's problem behaviors. Results favor a liability model that relates…