A study has shown that methylation of 1,8-dihydroxy-9,10-anthraquinone (1) with methyl tosylate is highly dependent upon reaction conditions. When the reaction is carried out by a simple heating of the reaction mixture without solvent it yields dimethyl product in a nearly quantitative yield and refluxing the same mixture of reactants in…

Since Robert Millikan discovered the quantization of electric charge and measured its fundamental value over 90 years ago, his oil-drop experiment has become essential in physics laboratory classes at both the high school and college level. As physics instructors, however, many of us have used the traditional setup and experienced the tedium of…

Active-learning strategies are increasingly being integrated into college-level science courses to make material more accessible to all students and to improve learning outcomes. One active-learning pedagogy, case-based learning (CBL), was developed as a way to both enhance engagement in the material and to accommodate diverse learning styles.…

The purpose of the paper is twofold: (1) To contrast the longstanding tradition of private and public courses of chemistry with the public demonstrations of physics. Whether taught in public institutions such as the Jardin du Roi or by apothecaries in their officines chemistry demonstrations were not for the entertainment of their audiences.…

In this article, the authors describe steps on how to develop a high-impact activity in which students build, test, and improve their own "coffee can" speakers to observe firsthand how loudspeakers work to convert electrical energy to sound. The activity is appropriate for students in grades three to six and lends itself best to students…

Many general physics laboratories involve the use of springs to demonstrate Hooke's law, and much ado is made about how this can be used as a model for describing the elastic characteristics of materials at the molecular or atomic level. In recent years, the proliferation of computers, and appropriate sensors, have made it possible to demonstrate…

The principles of magnetism are a common topic in most introductory physics courses, yet curricular materials exploring the behavior of permanent magnets and magnetic materials are surprisingly rare in the literature. We reviewed the literature to see how magnetism is typically covered in introductory textbooks and curricula. We found that while…

Protein kinase Cs (PKCs) are implicated in many forms of synaptic plasticity. However, the specific isoform(s) of PKC that underlie(s) these events are often not known. We have used "Aplysia" as a model system in order to investigate the isoform specificity of PKC actions due to the presence of fewer isoforms and a large number of documented…

We have developed two kinds of optical experiments: color mixture and fluorescence, using mini-torches with light emitting diodes (LEDs) that emit three primary colors. Since the tools used in the experiments are simple and inexpensive, students can easily retry and develop the experiments by themselves. As well as giving an introduction to basic…

Teaching science by means of inquiry-based projects has the potential to transform the science lab into a place of debate and discovery, but teachers run the risk of either leaving students to work too independently or forcing them to be too dependent on our guidance. To counter these challenges, the author implemented changes in the way topics…

This paper reports the modification of an existing experimental subject into a project laboratory for first-year physics students studying in the first cycle of university level and at a higher professional level. The subject is aimed at developing important science-related competences and skills through concrete steps under circumstances that are…

The role played by physical parameters governing the transport of heat in periodical time-varying phenomena within solids is discussed. Starting with a brief look at the conduction heat transport mechanism, the equations governing heat conduction under static, stationary and non-stationary conditions, and the physical parameters involved, are…

The Michelson interferometer is one of the best established tools for quantitative interferometric measurements. It has been, and is still successfully used, not only for scientific purposes, but it is also introduced in undergraduate courses for qualitative demonstrations as well as for quantitative determination of several properties such as…

This exercise integrates the infrared unknown identification ("IR-ID") experiment common to most organic laboratory syllabi with computer molecular modeling. In this modification students are still required to identify unknown compounds from their IR spectra, but must additionally match some of the absorptions with computed frequencies they…

SDS-PAGE is a simple, rapid technique that has many uses in biochemistry and is readily adaptable to the undergraduate laboratory. It is, however, a technique prone to several types of procedural pitfalls. This article describes the use of SDS-PAGE to determine the subunit molecular mass and composition of yeast alcohol dehydrogenase employing…