Elevated whole blood serotonin (WB5-HT) is a well-replicated biomarker in autism spectrum disorder (ASD). Decreased platelet serotonin receptor 5-HT[subscript 2A] binding has been reported in ASD. WB5-HT levels and platelet 5-HT[subscript 2A] specific binding were obtained from 110 individuals with ASD and 18 controls. Individuals with ASD had…

Several studies show altered heart rate variability (HRV) in autism spectrum disorder (ASD), but findings are neither universal nor specific to ASD. We apply a set of linear and nonlinear HRV measures--including phase rectified signal averaging--to segments of resting ECG data collected from school-age children with ASD, age-matched typically…

Metabolic systems form the very foundation of life and as such are broadly taught in the molecular life sciences. Here, we describe the biochemistry educator community-based development and use of an assessment instrument designed to evaluate students' ideas about metabolic pathway dynamics and regulation in undergraduate biochemistry courses.…

While metabolism is a fundamental process in physiology, the measurement of metabolism by living animals often requires specialized and expensive equipment. In 2016, I developed a novel laboratory exercise for animal physiology students where students were able to observe the effects of temperature and long-term temperature acclimation on the…

This study evaluated the reliability of the portable Lactate Pro 2 analyzer (LP2), and its validity compared to a laboratory-based analyzer, YSI 1500 Sport (YSI). Blood samples (n = 258) were collected during 44 graded incremental rowing tests, with data from 17 tests used to quantify load, heart rate, and oxygen consumption at lactate threshold.…

Students encounter antioxidants in many areas of their daily life. Antioxidants play a crucial role in cosmetics, in nutritional or dietary supplements, as additives for the preservation of food, and as a natural component in fruit and vegetables. Accordingly, antioxidants are believed to promote health through the prevention of oxidative stress…

Regulation is a key concept for understanding the dynamics of metabolism in bacteria. This report outlines a simple laboratory experiment aimed at studying a key form of regulation in bacterial metabolism, exemplifying how microbes switch the flux of carbon towards alternative metabolic fates as a function of nutrient availability and according to…

Enzymes are organic molecules known for their catalytic nature because they accelerate metabolic reactions in organisms. The study of enzyme functions and modes of action is essential to understand Biochemistry. This study aimed to analyse the acetylcholinesterase enzymatic activity, as well as the enzymatic inhibition mechanism in practical…

While psychologists often use a combination of physiological and self-reported data to examine the dynamic effects of stress on performance, the impact of affective states on Foreign Language (FL) speaking performance has almost exclusively been assessed using self-report methodology (e.g., questionnaires, interviews). In fact, studies that…

Puerperium may lead to memory and executive/attentional complaints that interfere with women's daily life. This might be prevented by dietary compounds, such as neuroprotective polyphenols. Their bioactivity depends on their effects on lipid metabolism in different tissues, such as the brain, fat, and breast. Thus, a polyphenol-related cognitive…

Metabolism is a challenging subject for bioscience students due to the intrinsic complexity of the metabolic network, as well as that of the overlapping mechanisms of metabolic regulation. Collaborative learning based on a problem-based learning approach can help students to successfully learn and understand metabolism. In the present article, we…

There is growing interest among educational researchers in using heart rate variability (HRV) as an index of children's capacity to regulate their physiological arousal. Links between HRV and young children's self-regulation have, however, been inconsistent, and there is limited research on children's HRV in learning-related contexts. HRV was…

Purpose: This systematic review aimed to identify studies evaluating the impact of high-intensity interval training when delivered in school and sports training. Methods: A systematic search of 10 databases (September 2019) identified 24 eligible studies (including children and/or adolescents 5-18 years and reporting cardiometabolic health and/or…

Probing children's understanding of science concepts has been a focus of research in science education since the 1980s. In the process of learning, learners often produce many conceptions that differ from established scientific knowledge, which are commonly labelled as alternative conceptions (ACs). Knowing these ACs, their prevalence, nature,…

Purpose: To compare the effects of a single bout of eccentric cycling (ECC) and eccentric cycling with blood flow restriction (ECC[subscript BFR]) on the changes in cardio-metabolic demand and indirect markers of muscle damage in healthy men. Method: Twenty-one young men (24.0 ± 3.2 y) were randomly allocated in two groups to perform a 30-min…