Student-built photometers are recognized as being useful tools in teaching laboratories that help students understand the concepts behind experimental measurements, and several devices have been reported that employ photoresistors as the detector of choice. We demonstrate here an improvement over these instruments and the analyses thereof,…

This laboratory experiment demonstrates the important utility of transition-metal complexes as catalysts in the addition reaction of carbon tetrabromide (CBr ) to select alkenes. This application offers students the opportunity to understand why transition-metal complexes are worth synthesizing. The experiment builds on fundamental theories…

This work describes the design, building, and testing of miniature, low-cost LED-LDR colorimeters for absorption-spectrophotometry experiments. It also describes using these colorimeters for simplified context-based-learning (CBL) activities in school teaching laboratories and for public-engagement events. The colorimeters are simple and robust,…

Understanding how to perform an enzyme assay is a critical learning skill in the undergraduate biochemistry curriculum. Students in biochemistry typically have been exposed to the use of NMR spectroscopy as a tool to determine chemical structure, but rarely are they exposed to the utility of NMR to evaluate enzyme kinetics. Furthermore, coverage…

Plants encounter several different threats that affect their well-being during the spring. With chemistry, plants may defend themselves from, for example, excess UV-radiation and herbivores. The defense compounds between plant species vary, which makes it possible to utilize chemistry in identifying the plant species. In this laboratory…

An operationally straightforward, project-like laboratory experiment has been developed in which students directly compare the reactivity of two heterocycles, a cyclic "O,O"-acetal (standard C-O protecting group) and a cyclic "N,O"-acetal (oxazolidine), toward sodium borohydride and methylmagnesium iodide. Students synthesize a…

This inquiry-based lesson gets students moving to simulate chemical reactions in a way that allows them to visualize, understand, and retain information about chemical reactions in the stratosphere. Students then look at scientific data and conduct research to understand trends in the data and the impact of chlorofluorocarbons (CFCs). These…

One dimensional (1-D)[superscript 1] H and [superscript 13]C NMR experiments are common tools used in undergraduate organic laboratories to characterize synthesized molecules. However, 1-D NMR spectra cannot always provide unambiguous structure determination. In research laboratories, advanced NMR spectroscopy methods are employed for structural…

Here, we developed an integrated course based on two dimensional-electrophoresis and spectrometry mass (2DE-MS) technique for undergraduate students to help them learn proteomic techniques. The soluble proteins in wild type and gene knockout bacteria were separated by 2DE and the differently expressed proteins were identified by MS analysis. The…

Microplastic contamination of the environment is a major concern but detecting such contamination presents a challenge, particularly for particles <0.1 mm in size. Community scientists and students who participated in a plankton monitoring program and routinely examined samples of seawater using brightfield microscopy, often found fragments and…

Mass spectrometers are ever-increasingly powerful, user-friendly, and affordable. Thus, the addition of mass spectrometry experiments into the undergraduate laboratory curriculum is now both feasible and an effective tool to introduce students to relevant instrumentation. Here an experiment demonstrating the use of a high-resolution electrospray…

A simple computer interface for controlling a compact spectrograph for use as a spectrophotometer in an undergraduate teaching laboratory was developed. The project was implemented on a Raspberry Pi computer which permits the integration of a light source into the software. The interface was written in Python to facilitate modification by the user…

Given student familiarity with electronic cigarettes (e-cigs), this lab uses a student-built smoke collection apparatus to collect e-cig vapors to teach students about gas chromatography-mass spectrometry (GC-MS). Students in a second semester, introductory organic chemistry course spent 1 week collecting e-cig vapors and 1 week qualitatively…

Analysis of stochastic processes can be used to engender critical thinking. Quantum dots have a reversible, stochastic transition between luminescent and nonluminescent states. The luminescence intermittency is known as blinking and is not evident from ensemble measurements. In order to stimulate critical thinking, students design, perform, and…

Demonstration of a colorimetric approach for nucleic acid detection represents an attractive educational experiment for chemistry undergraduate students in the time of coronavirus pandemic. Herein, a rapid and vivid detection method that visualizes the presence of a specific DNA sequence is described. The plasmon resonance of gold nanoparticles…