The application of chemistry concepts in biological settings plays an important role in the interdisciplinary field of drug discovery and development. This is true for molecular docking, where an understanding of intermolecular forces and noncovalent interactions is useful for rational drug design and development. Here we report the design and use…

Structure--activity relationships are foundational concepts in biochemistry and drug design. Despite their importance, it can be difficult to create and execute laboratory activities that allow students to directly observe the interactions between small-molecule drugs and their biomolecular targets. Here, we report an activity that investigates…

Success in general chemistry requires active engagement with course material. COVID-19 accelerated the move to online courses, creating a crucial need for engaging course activities. The Mysterious Compound chemistry game was designed to engage undergraduate students in introductory chemistry concepts while allowing the instructor and students to…

Cycloadditions in combination with multicomponent reactions are among the most valuable synthetic tools used by organic chemists to construct cyclic and heterocyclic compounds in a straightforward way. Although cycloadditions, such as the Diels--Alder reaction, are mainly covered in basic and advanced organic courses for undergraduate students,…

Laboratory automation and data science are valuable new skills for all chemists, but most pedagogical activities involving automation to date have focused on upper-level coursework. Herein, we describe a combined computational and experimental lab suitable for a first-year undergraduate general chemistry course, in which these topics are…

Density functional theory (DFT) is indubitably the most popular and among the most successful approaches for approximately solving the many-electron Schro¨dinger equation. The level of understanding on the part of both researchers and students using DFT, however, is lacking, given the availability of black-box software. The present work addresses…

The problem addressed in this study was some early elementary teachers have low self-efficacy about their scientific knowledge and ability to support children's scientific learning; consequently, they are less likely to dedicate instructional time to science. The purpose of this qualitative case study was to investigate how elementary school…

This dissertation investigates the complexities associated with developing expertise in physics problem-solving and the methods for measuring and assessing the skills involved. Problem-solving skills are critical in today's rapidly changing world, and thus, it is important to emphasize them in education. However, lacking precise methods for…

Text-to-speech (TTS) technology is a common accommodation available for students with disabilities. Despite the ubiquitous nature of TTS, this technology has not been explored in laboratory settings for neurodiverse college students. This study explores the adaptability of laboratory accessible TTS technology (originally developed for blind/low…

An understanding of statistical concepts is necessary for a chemist with a complete education. Here, statistical tests were taught using the R Commander and the Factoshiny packages. These packages run on R software and have a graphical user interface (GUI), which allows students to do statistical tests quickly and easily. These packages were…

Chemicals are characteristic of chemistry education practices at all educational levels. The aim of this study is to explore teachers' didactic rationales when reasoning about the use of chemicals in their teaching practice. Experienced upper secondary chemistry teachers in Sweden were interviewed about their considerations regarding why, when,…

Studies have demonstrated that visual-spatial skills correlate with student performance and success in science, technology, engineering, and math (STEM). The ability to reason with spatial information is essential for conceptual subjects like chemistry, a deep understanding of which requires dealing with the invisible world of atoms and molecules…

Silver and its compounds have been widely used in experimental teaching, industrial production, and other fields. In these processes, a large amount of wastewater containing silver is usually produced, which might contribute to environmental pollution. Therefore, recycling silver from wastewater not only has good economic value but also meets the…

The concept of relative density is introduced in the middle school and high school curricula by an intuitive approach based on the phenomena of immersion and flotation. In high school, the same concept is taught as the ratio between the masses of two bodies of the same volume. This dichotomy of the concept of relative density between the two…

The main difficulty in studying molecular symmetry is the mental manipulation of molecules when searching for symmetry. Numerous methods of teaching molecular symmetry require students to identify symmetry elements of objects or molecules. As an alternative, we propose activity that identifies symmetry using elements outside the objects, together…