A controlled trial of teaching clinical biochemistry by the Keller Plan at the University of Otago Medical School is described. The Keller Plan group performed significantly better than the control group on the final examination. (MLW)

Presents tabular information concerning recent research in the field of enzymes in analytic chemistry, with methods, substrate or reaction catalyzed, assay, comments and references listed. The table refers to 128 references. Also listed are 13 general citations. (CS)

The author suggests the use of chronobiology--the body's 24-hour cycle rhythms--to chart children's physical, emotional, and mental reactions in order to more realistically and productively structure learning activities. This exercise also involves math and science skills. (KC)

Summarizes what is known about the effects of marijuana use on health. The topics included are its chemistry and the metabolism; the effects of acute intoxication on learning, memory, intellectual performance, driving, and other skilled performances; and effects on lungs, brain, heart, and other systems. (SA)

This inexpensive but informative experiment for undergraduate biochemistry students involves isolating phosphatidyl choline from spinach leaves. Emphasis is on introducing students to techniques of lipid extraction, separation of lipids, identification using thin layer chromatography, and identification of fatty acids. Three periods of three hours…

Discusses experiences with the use of problem-based learning as applied to knowledge-rich biochemistry courses. Concludes that problem-based learning is not only effective in promoting habits of mind that support higher order thinking but also a powerful vehicle for conveying knowledge by imparting separate bits of knowledge as interconnected…

This action research study evaluated problem-based learning (PBL), traditional lecture, and a combination of PBL and lecture in an elective biochemistry course at a secondary school for gifted students. Lecture tended to wide content coverage, whereas understanding and retention was promoted by PBL. (Author/DB)

Describes an integrated problem-based learning experience for first-year medical students and assesses the effectiveness of the process in identifying basic science issues relevant to biochemical principles. (DDR)

Presents a science activity that integrates the disciplines of anatomy, physiology, genetics, and forensics in which students act as detectives unraveling evidence at a murder crime scene. This project is designed to enhance student interest by providing immediate application of these disciplines. (DKM)

Describes the biochemistry component of study to become a medical technologist in a Chilean university. Provides details of program structure, course content descriptions, and teaching strategies. (DDR)

The need to give high school students a more pragmatic grasp and understanding of technology, in addition to guidance concerning their career paths, is discussed. Described are the design, initiation, methods, topics and evaluation of this exploratory program. Recommendations for future implementation of similar programs are provided. (CW)

Develops an experiment that could be done in two- to three-hour blocks and does not rely on cold room procedures for most of the purification. Describes the materials, methods, and results of the purification of bovine heart lactate dehydrogenase using ammonium sulfate fractionation, dialysis, and separation using affinity chromatography and…

Described is an experiment which is designed to investigate the reaction of the protein ferrimyoglobin with fluoride. The activity uses readily available apparatus and the technique of optical absorbance for measurement of concentrations. Experimental design, procedures, and treatment of the equilibrium data are detailed. (CW)

Discusses a laboratory technique of enzyme purification by affinity chromatography as part of an undergraduate biochemical methodology course. Provides preparation details of the rat muscle homogenate and reagents. Proposes column requirements and assaying information. (MVL)

Explores neurochemical events in the extra cellular space of the brain by use of in vivo voltammetric microelectrodes. Reports dopamine concentrations and pathways, and discusses techniques used for analysis. Recognizes current problems and future directions for research. (ML)