An experiment is described that introduces students to the concept of temperature-dependent stability of the tetrahedral intermediate in an acyl-transfer reaction. The process involves the determination of the structure of an alpha-ketoester and its corresponding remarkably stable enol ester to suggest a mechanism for the formation of the products.

Electrophoresis is a valuable tool for biochemists, yet this technique is often not included in biochemistry laboratory curricula owing to time constraints or lack of equipment. Protein structure is also a topic of interest in many disciplines, yet most undergraduate lab experiments focus only on primary structure. In this experiment, students use…

A computational experiment is devised for advanced inorganic laboratory course that allows the students to explore the structure and bonding patterns of ethene and some heavier analogues. The HOMO-LUMO gaps, double bond dissociation energetics, and optimized geometries of ethene, disilene, and digermene are explored.

It is well known that reaction rates and physical properties of any substance depend on the temperature. Therefore, an accurate temperature measurement is a key factor for successful activities both in chemical laboratories and industrial plants. Although plenty of sensors can be adopted for temperature measurements, thermocouples are the most…

Inquiry-based learning is more work than passive learning, and there is a body of students who prefer to take the easier route. But there is also a body of students who wish to explore science. Two descriptive evolutionary experiments conducted by university freshman/sophomore biology majors, enrolled in General Zoology are described.

An experiment to initiate students into several features of gas chromatograph-mass spectrometers (GC-MS) through the study of branded and counterfeit perfumes is described. The experiment enables the students to appreciate the power of GC-MS in distinguishing between original and imitation perfumes, and in analyzing data with its application…

The aim of the mentioned experiment is to aid students in developing tactics for distinguishing between signals originating from fluorescence and light scattering. Also, the experiment provides students with a deeper understanding of the physicochemical bases of each phenomenon and shows that the techniques are actually related.

A simple and effective way of exposing chemistry students to some of the effects of scaling up an organic reaction is described. It gives the student an experience that may encounter in an industrial setting.

Makes a case for the assessment of investigations against the Concept of Evidence in written tests as a potentially more reliable and valid way of assessing the ideas used in all types of biology investigations, thus reducing the distorting effect of assessment on the curriculum. (Author/SOE)

In this article, the author shares some notes from her own experience of supporting and delivering many hands-on datalogging workshops and using a variety of datalogging systems. She hopes they will be useful to those with less experience. She has broken down the notes into two main areas: the practicalities and learning about datalogging.…

Teaching Newtonian physics involves the replacement of students' ideas about physical situations with precise concepts appropriate for mathematical applications. This paper focuses on the concepts of "matter" and "mass". We suggest that students, like some pre-Newtonian scientists we examine, use these terms in a way that conflicts with their…

Piaget's investigations into children's understanding of the laws governing the movement of a simple pendulum were first reported in 1955 as part of a report into how children's knowledge of the physical world changes during development. Chapter 4 of Inhelder & Piaget (1955/1958) entitled "The Oscillation of a Pendulum and the Operations of…

Researchers at National Jewish Medical and Research Center have demonstrated that dilute bleach not only kills common household mold, but may also neutralize the mold allergens that cause most mold-related health complaints. The study, published in the Journal of Allergy and Clinical Immunology, is the first to test the effect on allergic…

Most students consume fizzy drinks and will have seen the bubbles that appear when the drinks are poured. But how much gas is in the bottle or can? Simple investigations can answer this and other questions both theoretically and experimentally.

A study involves multiple chemistry and physics concepts applied to a state of matter that has biological relevance. An experiment involving the synthesis and physical properties of liquid crystals illustrates the interdisciplinary nature of liquid crystal research and the practical devices derived from such research.