This dissertation presents my explorations in both molecular biology and science education research. In study one, we determined the "ADIPOQ" and "ADIPORI" genotypes of 364 White and 148 Black BrCa patients and used dominant model univariate logistic regression analyses to determine individual SNP and haplotype associations…

In January 2011, a Joint Committee of representatives from the U.S. Department of Education (ED) and the U.S. National Science Foundation (NSF) began work to establish cross-agency guidelines for improving the quality, coherence, and pace of knowledge development in science, technology, engineering and mathematics (STEM) education. Although the…

Objective: To analyse teachers' health views in order to obtain general trends in factors influencing health and health education and to fit them into the negative-positive model of health proposed by Downie and collaborators. Method: This large international study involved 15 countries from Western and Eastern Europe, North and Sub-Saharan…

The aim of this study is to compare the effectiveness of models of programmed instruction and conventional (informative-illustrative) expository teaching in terms of fulfilling the aims of the course "Human anatomy and physiology" which is included in the physiology programme and designed for undergraduate students majoring in biology…

This document describes a solution to a problem in the automatic content scoring of the multilingual character-by-character highlighting item type. This solution is language independent and represents a significant enhancement. This solution not only facilitates automatic scoring but plays an important role in clustering students' responses;…

The increasing expectations for all incoming faculty to not only produce exceptional research, but also be better communicators and educators immediately has put the pressure on graduate students looking to move into academia to improve on their ability to teach. By providing the opportunity for Masters and PhD level students, the Departments of…

The subject of this inquiry is to explore university students' stories of transformation from the practice of integral yoga in an undergraduate course exploring human biology, health, and spirituality. The stories of participants give evidence for successful educational performance when yoga and meditation are combined with academic learning in…

This study investigated Ontario science and biology teachers' practices and attitudes toward animal dissection and dissection alternatives. The data was collected through a mixed methods approach involving online surveys (n = 153) and subsequent telephone interviews (n = 9) with secondary school science and biology teachers. The findings indicate…

The authors examine the effects of poverty-related adversity on child development, drawing upon psychobiological principles of experiential canalization and the biological embedding of experience. They integrate findings from research on stress physiology, neurocognitive function, and self-regulation to consider adaptive processes in response to…

A substantial body of literature has highlighted many factors that impede faculty change, the most common of which are a lack of training, time, and incentives. However, there may be other barriers--unacknowledged and unexamined barriers--that might prove to be equally important. In particular, the tensions between a scientist's professional…

The author has spent six years teaching high school science in Southeast Portland. It is located in the heart of the largest immigrant area in the city, and at least 80 percent of the students qualify for free or reduced lunch. Every day she witnesses how poverty and language barriers create serious challenges in her students' lives. Many students…

For many years, it has been suggested that drugs that interfere with dopamine (DA) transmission alter the "rewarding" impact of primary reinforcers such as food. Research and theory related to the functions of mesolimbic DA are undergoing a substantial conceptual restructuring, with the traditional emphasis on hedonia and primary reward yielding…

Specific genetic syndromes affect individuals' sexual development, experiences, and fertility. Individuals with specific syndromes can also display inappropriate sexual behavior resulting from vulnerabilities presented by their genetic makeup. Using clinical case studies, we discuss the specific impact that Down, Prader-Willi, and Williams…

The use of assessment methods is a widely discussed topic in education. Exams that are commonly used, however, may not necessarily assess student understanding at a high cognitive level. By implementing alternative assessment methods, instructors can influence student learning. Portfolio-based assessment (PBA) is a purposeful collection of student…

Estrogenic hormones exert their effects through binding to Estrogen Receptors (ERs), which work in concert with coregulators and extranuclear signaling pathways to control gene expression in normal as well as cancerous states, including breast tumors. In this thesis, we have used multiple genome-wide analysis tools to elucidate various ways that…