This investigative laboratory activity engages students in observing, recording, graphing and analyzing pulsation rates in a commonly used laboratory organism, blackworms. This activity stresses how various drugs can impact the pulsation rate in blackworms at varying concentrations. In addition, we have incorporated two new ways to view the…

The "Next Generation Science Standards" (NGSS) stress the need for all students to receive excellent science instruction--including those with disabilities--based upon disciplinary core ideas, crosscutting concepts, and science and engineering practices (NGSS Lead States 2013). Further, the NGSS emphasize reducing disparities in student…

This two-period undergraduate laboratory experiment involves the synthesis of a mixture of isomeric unknowns, isolation of the mixture by means of distillation, and characterization of the two products primarily by NMR spectroscopy (1D and 2D) supported with IR spectroscopy and GC-MS techniques. Subsequent calculation and examination of the…

For many students, the first--and sometimes only--chance to look through a microscope is in high school biology class, where they observe plant and animal cells up close. Even in college, few students use a microscope for a subject other than biology. Thus, it can be a surprise to learn that microscopes are a primary tool used to understand the…

This lab experiment uses [superscript 31]P NMR spectroscopy of biomolecules to determine pK[subscript a] values and the binding energies of metal/biomolecule complexes. Solutions of adenosine nucleotides are prepared, and a series of [superscript 31]P NMR spectra are collected as a function of pH and in the absence and presence of magnesium or…

pH determination is an essential experiment in many chemistry laboratories. It requires a potentiometric instrument with extremely low input bias current to accurately measure the voltage between a pH sensing electrode and a reference electrode. In this technology report, we propose an open-source potentiometric instrument for pH determination…

In hydrostatics, pressure measurement with U-gauges and their relationship to density is a well-known experiment. Very little is studied or experimented with the dynamics of the movement of a liquid in a U-tube probably due to its theoretical complexity but, after all, it is a simple damped oscillating system. In this paper we present a relatively…

The growing movement in STEM education is popularizing active learning, which has benefits for high school and undergraduate students, especially those in rural areas with limited resources. In Mississippi, daunting health disparities in incidence of stroke, cardiovascular disease, type II diabetes, and obesity warrant the implementation of…

This laboratory experiment utilizes an exploration of the storage stability of beer to introduce basic aspects of electron-paramagnetic-resonance (EPR) spectroscopy. Radicals formed upon aerobic forced-aging of beer samples are established by using a spin-trap. The students are introduced to basic principles of EPR spectroscopy and food and…

This two-part laboratory experiment is concerned with investigating key aspects of the Suzuki-- Miyaura cross-coupling reaction. The first part of this experiment utilizes high-throughput experimentation techniques to reinforce, explore, and extend fundamental concepts that are presented in the classroom. In contrast, the second part employs…

Histotechnology is commonly used in medical research, pathological testing, and pharmaceutical development. We designed a three-week, inquiry-based laboratory module that helps prepare students for biomedical careers by teaching them tissue sampling, processing, and imaging. Rats were treated with streptozotocin (a known diabetogen) while control…

Aim/Purpose: This paper provides a general-purpose categorization scheme for assessing the utility of new and emerging three-dimensional interactive digital environments (3D-IDEs), along with specific pedagogic approaches that are known to work. It argues for the use of 3D-IDEs on the basis of their ludic appeal and ability to provide intrinsic…

The MicRoboCop project introduces chemistry students to the concepts and protocols of synthetic biology. MicRoboCop is a biosensor that has been designed for unique applications in forensic chemistry. The lab is carried out in collaboration with an instructor teaching a genetics course. Students in the biology course synthesize biosensors using…

Lactase is the enzyme responsible for the digestion of the disaccharide lactose, and deficiency in this enzyme causes the prevalent medical condition lactose intolerance. Management of lactose intolerance can be achieved through the administration of lactase supplements. Lactase is an appropriate platform for advanced enzymatic study because its…

According to variation theory, it is essential to enable students to focus on the object of learning and discern its critical features, but the features that "it is possible" to discern often depend on the equipment used. Thus, in labs, the experimental technologies used may shape students' experience of focal phenomena, in a…