When implemented well, centralized enrollment systems can boost overall enrollment in publicly funded care and education programs, decrease the burden placed on families, diversify enrollment across early childhood programs, improve and streamline communication with families and providers, and reduce the administrative load for providers. This brief discusses what centralized enrollment is and why early care and education leaders might pursue it. Then, it describes different approaches to implementing centralized enrollment and how lessons learned might apply to other communities. These tactical lessons come from the recently relaunched Early Care and Education (ECE) Implementation Working Group. Other briefs created from the working group's findings include "Family Outreach for Early Education Enrollment: A Powerful Programmatic and Political Tool," which explores the role of family outreach in enrollment, and "Participatory Planning to Build Stronger Early Childhood Policy and Programs," which advocates for the participation of people in policymaking.