When neurologically normal individuals bisect a horizontal line as accurately as possible, they reliably show a slight leftward error. This leftward inaccuracy is called "pseudoneglect" because errors made by neurologically normal individuals are directionally opposite to those made by persons with visuospatial neglect (Jewell & McCourt, 2000). In…

Why females generally perform better on language tasks than males is unknown. Sex differences were here identified in children (ages 9-15) across two linguistic tasks for words presented in two modalities. Bilateral activation in the inferior frontal and superior temporal gyri and activation in the left fusiform gyrus of girls was greater than in…

Increased variability in reaction time (RT) has been proposed as a cardinal feature of attention deficit hyperactivity disorder (ADHD). Increased variability during sustained attention tasks may reflect inefficient fronto-striatal and fronto-parietal circuitry; activity within these circuits is modulated by the catecholamines. A disruption to…

Relatively little is known about the functional development of verbal and nonverbal working memory during adolescence. Behavioral studies have demonstrated that WM capacity increases with age, yet relatively few studies have assessed the relationship between brain-activity and age-related changes in WM capacity, especially as it differs across…

Since the earliest descriptions of individuals with autism spectrum disorders (ASDs) abnormalities in affective behaviours have been considered a prominent feature in their clinical manifestations. What remains unclear, however, is whether these altered emotional behaviours are a mere facet of abnormalities in socio-cognitive processes or whether…

A high prevalence of deficits in explicit learning has been reported for schizophrenic patients, but it is less clear whether these patients are impaired in implicit learning. Deficits in implicit learning indicative of a fronto-striatal dysfunction have been reported using a serial reaction-time task (SRT), but the impact of typical neuroleptic…

Pseudoneglect is traditionally viewed as reflecting right hemisphere specialization for processing spatial information, which brings about relatively greater activation of the right hemisphere and orienting towards the contralateral space. Such interpretation implies that the leftward attentional bias is a population trait. Animal studies,…

The event specificity of autobiographical memories refers to the degree to which retold memories include specific details about a unique personal experience from a variety of representational systems supported by different brain areas. This article proposes 2 text measures as indicators of event specificity: (a) a measure of temporal sequence in…

Background: There is increasing interest in applying neuroscience findings to topics in education. Purpose: This application requires a proper conceptualization of the relation between cognition and brain function. This paper considers two such conceptualizations. The area focus understands each cognitive competency as the product of one (and only…

The implementation of standards and high-stakes testing has increased the pressure on classroom teachers to cover content in what seems like an ever-shrinking period of time. What if there was a way to help students pay better attention and remember more of their learning that could also reduce teacher stress? This article describes one way to…

The neurobiological systems which underlie emotion attribution among female patients with Fragile X (FraX) syndrome are examined. Results show that the emotion circuit which regulates responses to facial stimuli is potentially disrupted among female subjects with FraX syndrome. Anterior cingulate cortex activity in female subjects with FraX…

Adult learning and memory functions are strongly dependent on neonatal experiences. We recently showed that neonatal odor-shock learning attenuates later life odor fear conditioning and amygdala activity. In the present work we investigated whether changes observed in adults can also be observed in other structures normally involved, namely…

Despite many disagreements on the utility of neuropsychological applications in schools, executive function measures have been found to be useful across a variety of areas and ages. In addition, many disagreements are extant in discussions of the maturational course of the development of executive functioning abilities that are dependent on…

Patients with conduction aphasia have been characterized as having a short-term memory deficit that leads to relative difficulty on span and repetition tasks. It has also been observed that these same patients often get the gist of what is said to them, even if they are unable to repeat the information verbatim. To study this phenomenon…

Catechol-O-methyltransferase (COMT) is a methylation enzyme that catalyzes the degradation pathway and inactivation of dopamine. It is accepted widely as being involved in the modulation of dopaminergic physiology and prefrontal cortex (PFC) function. The COMT Val158Met polymorphism is associated with variation in COMT activity. COMT 158Met allele…